Is COVID-19 associated with latent toxoplasmosis?

被引:0
作者
Salman Ghaffari
Narges Kalantari
Tahmineh Gorgani-Firouzjaee
Masomeh Bayani
Farzaneh Jalali
Meysam Aghajani Daroonkola
机构
[1] Babol University of Medical Sciences,Department of Parasitology and Mycology, School of Medicine
[2] Health Research Institute,Cellular and Molecular Biology Research Centre
[3] Babol University of Medical Sciences,Infectious Diseases and Tropical Medicine Research Centre
[4] Babol University of Medical Sciences,Laboratory Sciences Group, Faculty of Para
[5] Babol University of Medical Sciences,Medicine
[6] Babol University of Medical Sciences,Shahid Yahyanejad Hospital
来源
Environmental Science and Pollution Research | 2021年 / 28卷
关键词
COVID-19; Seroprevalence; Toxoplasmosis;
D O I
暂无
中图分类号
学科分类号
摘要
The present study aimed to evaluate the possible association between coronavirus disease 2019 (COVID-19) and latent Toxoplasma gondii infection in a group of patients and healthy individuals. Blood samples were obtained from 269 PCR-positive COVID-19 patients. The serum was separated and tested for the existence of anti-T. gondii antibodies (IgG) using a commercial enzyme-linked immunosorbent assay kit. The prevalence of latent toxoplasmosis between a subgroup of the patients (aged under 55 years old) and COVID-19 negative individuals was compared. Anti-T. gondii antibodies were found in 226/269 (84.0%) patients with COVID-19. Anti-Toxoplasma antibodies were detected in 72/91 (79.1%) cases and 96/123 (78.0%) COVID-19 negative individuals (odd ratio = 1.1; 95% confidence interval: 0.55–2.07, P = 0.85). The median and interquartile range (IQR) of the IgG titer were not statistically significant different between case (97.3 [31.0–133.5]) and control groups (34.4 [13.0–144.5]) (P = 0.10). These findings demonstrated that latent Toxoplasma infection is prevalent amongst the COVID-19 patients. It also did not find any significant association between chronic toxoplasmosis and COVID-19.
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页码:67886 / 67890
页数:4
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