Neuropathy and diabetic foot ulcers

被引:2
作者
Lobmann, R. [1 ]
机构
[1] Klinikum Stuttgart Burgerhosp, Klin Endokrinol Diabetol & Geriatrie, D-70191 Stuttgart, Germany
来源
INTERNIST | 2015年 / 56卷 / 05期
关键词
Diabetes mellitus; Wound healing; Polyneuropathies; Foot ulcer; Amputation; NERVE GROWTH-FACTOR; MATRIX-METALLOPROTEINASES; AMPUTATION RATE; PREVENTION; EXPRESSION; WOUNDS; MANAGEMENT; CARE; SKIN;
D O I
10.1007/s00108-014-3630-7
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Diabetic foot ulceration is a serious complication of diabetes mellitus worldwide and the most common cause of hospitalization in diabetic patients. The etiology of diabetic foot ulcerations is complex due to their multifactorial nature. Polyneuropathy plays an important role in the pathophysiology of diabetic foot ulceration. Proper adherence to standard treatment strategies and interdisciplinary cooperation can reduce the high rates of major amputations.
引用
收藏
页码:503 / 512
页数:10
相关论文
共 54 条
[1]   Motor dysfunction in diabetes [J].
Andersen, Henning .
DIABETES-METABOLISM RESEARCH AND REVIEWS, 2012, 28 :89-92
[2]   Wound healing in denervated tissue [J].
Barker, Allison R. ;
Rosson, Gedge D. ;
Dellon, A. Lee .
ANNALS OF PLASTIC SURGERY, 2006, 57 (03) :339-342
[3]  
Bentley Jenny, 2007, Br J Community Nurs, V12, ppassim
[4]  
Boucek Petr, 2006, Review of Diabetic Studies, V3, P143, DOI 10.1900/RDS.2006.3.143
[5]   Neuropathic diabetic foot ulcers [J].
Boulton, AJM ;
Kirsner, RS ;
Vileikyte, L .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (01) :48-55
[6]   The diabetic foot: grand overview, epidemiology and pathogenesis [J].
Boulton, Andrew J. M. .
DIABETES-METABOLISM RESEARCH AND REVIEWS, 2008, 24 :S3-S6
[7]  
Boulton Andrew J M, 2014, Handb Clin Neurol, V126, P97, DOI 10.1016/B978-0-444-53480-4.00008-4
[8]   The Pathway to Foot Ulceration in Diabetes [J].
Boulton, Andrew J. M. .
MEDICAL CLINICS OF NORTH AMERICA, 2013, 97 (05) :775-+
[9]   What you can't feel can hurt you [J].
Boulton, Andrew J. M. .
JOURNAL OF VASCULAR SURGERY, 2010, 52 :28S-30S
[10]   Expression of matrix metalloproteinases, cytokines, and connexins in diabetic and nondiabetic human keratinocytes before and after transplantation into an ex vivo wound-healing model [J].
Brandner, Johanna M. ;
Zacheja, Steffi ;
Houdek, Pia ;
Moll, Ingrid ;
Lobmann, Ralf .
DIABETES CARE, 2008, 31 (01) :114-120