Short-Term Contact Kinematic Changes and Longer-Term Biochemical Changes in the Cartilage After ACL Reconstruction: A Pilot Study

被引：0
作者：
Guoan Li
Jing-Sheng Li
Martin Torriani
Ali Hosseini
机构：
[1] Newton-Wellesley Hospital and Harvard Medical School,Orthopaedic Bioengineering Research Center
[2] Boston University,College of Health and Rehabilitation Sciences
[3] Massachusetts General Hospital and Harvard Medical School,Division of Musculoskeletal Imaging and Intervention, Department of Radiology
来源：
Annals of Biomedical Engineering | 2018年 / 46卷
关键词：
ACL; ACL reconstruction; Cartilage degeneration; Prognostic marker; Kinematics; Knee;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Investigation of the development of cartilage degeneration after ACL reconstruction is important for improving current surgical treatment of ACL injuries to prevent long-term knee joint degeneration. This pilot study examined the relationship between the changes in weight-bearing knee contact kinematics 6 months after ACL reconstruction and the biochemical composition changes in the knee cartilage measured using T2 relaxation values 3 years after the surgery in seven patients. The analysis indicated that the change of the knee contact kinematics in short-term after ACL reconstruction is associated with an increase of T2 values of the cartilage in longer follow up times. The data of this study could provide preliminary data to power future studies that use prospective, longitudinal research and large patient populations to establish prognostic biomechanical markers for determination of long-term cartilage degeneration after ACL reconstruction.
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页码：1797 / 1805
页数：8
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