Hepatitis B vaccination coverage among healthcare workers at a tertiary hospital in Rwanda

被引：11

作者：

Muvunyi C.M. ^{[1
]}

Harelimana J.D.D. ^{[2
]}

Sebatunzi O.R. ^{[3
]}

Atmaprakash A.C. ^{[4
]}

Seruyange E. ^{[3
]}

Masaisa F. ^{[1
,3
]}

Manzi O. ^{[3
]}

Nyundo M. ^{[4
]}

Hategekimana T. ^{[4
]}

机构：

[1] Department of Clinical Biology, School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali

[2] Department of Biomedical Laboratory Science, School of Health Science, College of Medicine and Health Sciences, University of Rwanda, Kigali

[3] Department of Internal Medicine, School of Medicine and Pharmacy, College of Medicine and Health Sciences, University of Rwanda, Kigali

[4] Kigali University Teaching Hospital, Kigali

来源：

BMC Research Notes | / 11卷 / 1期

关键词：

Health care workers; Hepatitis B; Immune response; Vaccination;

D O I：

10.1186/s13104-018-4002-5

中图分类号：

学科分类号：

摘要：

Objective: We evaluated post-vaccination immunity status and describe potential risk factors associated with the lack of response among healthcare workers (HCWs) at a tertiary care hospital in Kigali, Rwanda. Results: Of 373 HCWs, 291 (78.2%) were female and 81 (21.8%) were male. The mean age of the study participants was 40.2 years (standard deviation [SD], 7.7 years), within a range of 24-41 years. Participants' mean BMI was 25.4 ± 6.6 kg/m 2 , with more than half of patients (60.3%) being overweight. 96% received all three doses of vaccination. A total of 36 participants (9.6%) were considered non responders as they did not develop a sufficient anti-HBs response post vaccination. The anti-HBs response was significantly higher in females when compared to males (p = 0.02). Interestingly, there was no significant association between decline in antibody levels with age (p = 0.242) and BMI (p = 0.516) of the participants. The anti-HBs titers were similar in the group of participants who had received two doses and those who had received three doses of the HBV vaccination. Overall the findings of our study provide a basis for testing for anti-HBs in all HCWs post vaccination in Rwanda. © 2018 The Author(s).

引用

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