Role of toll-like receptors in tissue repair and tumorigenesis

被引：0
|
作者：
S. Rakoff-Nahoum
R. Medzhitov
机构：
[1] Yale University School of Medicine,Howard Hughes Memorial Institute and Department of Immunobiology
来源：
Biochemistry (Moscow) | 2008年 / 73卷
关键词：
Toll-like receptors; tissue repair; tumorigenisis;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Toll-like receptors (TLRs) play a critical role in host defense from microbial infection. TLRs recognize conserved molecular structures produced by microorganisms and induce activation of innate and adaptive immune responses. The inflammatory responses induced by TLRs play an important role TLRs not only in host defense from infection, but also in tissue repair and regeneration. This latter function of TLRs can also contribute to tumorigenesis. Here we review recent progress in understanding the role of TLRs in cancer development.
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页码：555 / 561
页数：6
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