Intraperitoneal Drug Delivery of Antineoplastics

被引:0
作者
Maurie Markman
机构
[1] The Cleveland Clinic Foundation,The Cleveland Clinic Taussig Cancer Center, Department of Hematology/Medical Oncology
来源
Drugs | 2001年 / 61卷
关键词
Ovarian Cancer; Paclitaxel; Antineoplastic Agent; Advanced Ovarian Cancer; Regional Therapy;
D O I
暂无
中图分类号
学科分类号
摘要
The administration of antineoplastic agents directly into the peritoneal cavity as treatment of localised cancer is based on sound pharmacokinetic principles. This unique technique has to the potential to optimise outcome in settings where preclinical and clinical data suggest that cytotoxicity of a specific drug against a particular tumour type is enhanced by either increasing the drug concentration or duration of exposure.
引用
收藏
页码:1057 / 1065
页数:8
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