Hypercohones A–C, acylphloroglucinol derivatives with homo-adamantane cores from Hypericum cohaerens

被引:23
作者
Liu X. [1 ,2 ]
Yang X.-W. [1 ,2 ]
Chen C.-Q. [1 ]
Wu C.-Y. [1 ]
Zhang J.-J. [1 ,2 ]
Ma J.-Z. [1 ]
Wang H. [1 ]
Zhao Q.-S. [1 ]
Yang L.-X. [1 ]
Xu G. [1 ]
机构
[1] State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming
[2] University of Chinese Academy of Sciences, Beijing
关键词
acylphloroglucinol; adamantane; hypercohone; Hypericum cohaerens;
D O I
10.1007/s13659-013-0032-9
中图分类号
学科分类号
摘要
Three new homo-adamantanyl type natural products were derived from polyprenylated polycyclic acylphloroglucinol. Hypercohones A-C (1–3), along with five other known hypercohones (4–8), were isolated from the aerial parts of Hypericum cohaerens. The structures of 1–3 were elucidated on the basis of comprehensive spectroscopic analysis. The inhibitory activities of these isolates against five human cancer cell lines in vitro were tested. [Figure not available: see fulltext.]. © 2013, The Author(s).
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页码:233 / 237
页数:4
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