The evolutionary journey of Argonaute proteins

被引:0
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作者
Daan C Swarts
Kira Makarova
Yanli Wang
Kotaro Nakanishi
René F Ketting
Eugene V Koonin
Dinshaw J Patel
John van der Oost
机构
[1] Laboratory of Microbiology,Department of Agrotechnology and Food Sciences
[2] Wageningen University,Department of Chemistry and Biochemistry
[3] National Center for Biotechnology Information,undefined
[4] National Library of Medicine,undefined
[5] National Institutes of Health,undefined
[6] Institute of Biophysics,undefined
[7] Chinese Academy of Sciences,undefined
[8] Ohio State University,undefined
[9] Institute for Molecular Biology,undefined
[10] Structural Biology Program,undefined
[11] Memorial Sloan-Kettering Cancer Center,undefined
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摘要
Recent structural progress on prokaryotic and eukaryotic Argonaute proteins is reviewed here, along with the insights obtained into guide and target binding and target cleavage. Comprehensive phylogenetic analyses lead to a map of Argonaute's evolutionary paths, relating structural features and physiological roles.
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页码:743 / 753
页数:10
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