Objective Metrics of Ocular Surface Disease in Contact Lens Wearers: Meibography

被引:0
作者
Qazi Y. [1 ]
Hamrah P. [1 ]
机构
[1] Ocular Surface Imaging Center, Corneal & Refractive Surgery Service, Massachusetts Eye and Ear Infirmary, Department of Ophthalmology, Harvard Medical School, 243 Charles Street, Boston, 02114, MA
关键词
Contact lens; Dry eye; Imaging; Infrared meibography; Meibomian glands; Non-contact meibography; OCT meibography;
D O I
10.1007/s40135-015-0069-5
中图分类号
学科分类号
摘要
Dry eye symptoms are very prevalent in contact lens wearers and are most commonly attributed to evaporative dry eye (EDE) due to alterations in the quality of the pre-lens tear film lipids. Meibomian gland dysfunction (MGD), the most common cause of EDE, may result in contact lens-associated dry eye and ultimately to intolerance to contact lens wear. Thus, a thorough assessment of meibomian glands and the eyelid margin prior to and during contact lens wear may ensure continuous contact lens tolerance and the maintenance of a healthy ocular surface. Since meibomian glands are not overtly visible on slit-lamp biomicroscopy, imaging methods such as infrared meibography could play an important role in the evaluation of meibomian gland health. This review discusses the most pertinent advances in infrared meibography and its application to contact lens wearers, with a focus on the utility of quantitative imaging methods in the evaluation of meibomian glands. © 2015, Springer Science + Business Media New York.
引用
收藏
页码:122 / 131
页数:9
相关论文
共 65 条
[61]  
Ibrahim O.M., Matsumoto Y., Dogru M., Adan E.S., Wakamatsu T.H., Goto T., Et al., The efficacy, sensitivity, and specificity of in vivo laser confocal microscopy in the diagnosis of meibomian gland dysfunction, Ophthalmology, 117, 4, pp. 665-672, (2010)
[62]  
Matsumoto Y., Sato E.A., Ibrahim O.M., Dogru M., Tsubota K., The application of in vivo laser confocal microscopy to the diagnosis and evaluation of meibomian gland dysfunction, Mol Vis, 14, pp. 1263-1271, (2008)
[63]  
Kobayashi A., Yoshita T., Sugiyama K., In vivo findings of the bulbar/palpebral conjunctiva and presumed meibomian glands by laser scanning confocal microscopy, Cornea, 24, 8, pp. 985-988, (2005)
[64]  
Nelson J.D., Shimazaki J., Benitez-del-Castillo J.M., Craig J.P., McCulley J.P., Den S., Et al., The international workshop on meibomian gland dysfunction: report of the definition and classification subcommittee, Invest Ophthalmol Vis Sci, 52, 4, pp. 1930-1937, (2011)
[65]  
Li P., Johnstone M., Wang R.K., Full anterior segment biometry with extended imaging range spectral domain optical coherence tomography at 1340 nm, J Biomed Opt, 19, 4, (2014)