Role of tyrosine phosphorylation in sperm capacitation/acrosome reaction

被引:222
|
作者
Naz R.K. [1 ]
Rajesh P.B. [1 ]
机构
[1] Division of Research, Department of Obstetrics/Gynecology, Medical College of Ohio, Toledo, OH
关键词
Tyrosine Phosphorylation; Sperm Cell; Sperm Motility; Seminal Plasma; Zona Pellucida;
D O I
10.1186/1477-7827-2-75
中图分类号
学科分类号
摘要
Capacitation is an important physiological pre-requisite before the sperm cell can acrosome react and fertilize the oocyte. Recent reports from several laboratories have amply documented that the protein phosphorylation especially at tyrosine residues is one of the most important events that occur during capacitation. In this article, we have reviewed the data from our and other laboratories, and have constructed a heuristic model for the mechanisms and molecules involved in capacitation/acrosome reaction. © 2004 Naz and Rajesh; licensee BioMed Central Ltd.
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页数:12
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