Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs

Downes CP(2005)Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism Diabetes 54 617-623

Hundal HS(1995)Involvement of phosphorylase kinase inhibition in the effect of resorcinol and proglycosyn on glycogen metabolism in the liver Eur J Biochem 234 301-307

Rattigan S(1998)Induction of DNA synthesis in primary cultures of rat hepatocytes by serotonin: possible involvement of serotonin S2 receptor Hepatology 27 62-66

Dora KA(1989)Altered interactions between glycogenesis and lipid synthesis after liver resection: specific effects of liver regeneration, coupled with non-specific effects of surgery Clin Sci (Lond) 76 317-322

Colquhoun EQ(1984)Control of glycogen synthase phosphorylation in isolated rat hepatocytes by epinephrine, vasopressin and glucagon Eur J Biochem 142 511-520

Clark MG(2002)DARPP-32 mediates serotonergic neurotransmission in the forebrain Proc Natl Acad Sci USA 99 3188-3193

Moore MC(1997)The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action J Biol Chem 272 29698-29703

Geho WB(1999)Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons Nature 402 669-671

Lautz M(1999)Pharmacokinetics and tissue distribution of olanzapine in rats Biopharm Drug Dispos 20 369-377

Farmer B(1991)Improvement of insulin-induced glucose disposal in obese patients with NIDDM after 1-wk treatment with d-fenfluramine Diabetes Care 14 325-332

Downes CP(2005)Increased potency and efficacy of combined phosphorylase inactivation and glucokinase activation in control of hepatocyte glycogen metabolism Diabetes 54 617-623

Hundal HS(1995)Involvement of phosphorylase kinase inhibition in the effect of resorcinol and proglycosyn on glycogen metabolism in the liver Eur J Biochem 234 301-307

Rattigan S(1998)Induction of DNA synthesis in primary cultures of rat hepatocytes by serotonin: possible involvement of serotonin S2 receptor Hepatology 27 62-66

Dora KA(1989)Altered interactions between glycogenesis and lipid synthesis after liver resection: specific effects of liver regeneration, coupled with non-specific effects of surgery Clin Sci (Lond) 76 317-322

Colquhoun EQ(1984)Control of glycogen synthase phosphorylation in isolated rat hepatocytes by epinephrine, vasopressin and glucagon Eur J Biochem 142 511-520

Clark MG(2002)DARPP-32 mediates serotonergic neurotransmission in the forebrain Proc Natl Acad Sci USA 99 3188-3193

Moore MC(1997)The regulation of glycogen synthase by protein phosphatase 1 in 3T3-L1 adipocytes. Evidence for a potential role for DARPP-32 in insulin action J Biol Chem 272 29698-29703

Geho WB(1999)Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons Nature 402 669-671

Lautz M(1999)Pharmacokinetics and tissue distribution of olanzapine in rats Biopharm Drug Dispos 20 369-377

Farmer B(1991)Improvement of insulin-induced glucose disposal in obese patients with NIDDM after 1-wk treatment with d-fenfluramine Diabetes Care 14 325-332