Gigantol inhibits Wnt/β-catenin signaling and exhibits anticancer activity in breast cancer cells

被引：0
作者：
Shubin Yu
Zhongyuan Wang
Zijie Su
Jiaxing Song
Liang Zhou
Qi Sun
Shanshan Liu
Shiyue Li
Ying Li
Meina Wang
Guo-Qiang Zhang
Xue Zhang
Zhong-Jian Liu
Desheng Lu
机构：
[1] Shenzhen University Health Science Center,Guangdong Key Laboratory for Genome Stability & Disease Prevention, Cancer Research Center, Department of Pharmacology
[2] Shenzhen Key Laboratory for Orchid Conservation and Utilization,School of Traditional Chinese Materia Medica
[3] The National Orchid Conservation Center of China and The Orchid Conservation and Research Center of Shenzhen,undefined
[4] Shenyang Pharmaceutical University,undefined
来源：
BMC Complementary and Alternative Medicine | / 18卷
关键词：
Gigantol; LRP6; Wnt/β-catenin signaling; Breast cancer; Anticancer activity;
D O I：
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  • [1] Klaus A(2008)Wnt signalling and its impact on development and cancer Nat Rev Cancer 8 387-398
  • [2] Birchmeier W(2012)Wnt/beta-catenin signaling and disease Cell 149 1192-1205
  • [3] Clevers H(2009)Relaxant and antispasmodic effects of extracts of the orchid Encyclia Michuacana on isolated guinea pig ileum J Nat Med 63 65-68
  • [4] Nusse R(2010)KRAS, hedgehog, Wnt and the twisted developmental biology of pancreatic ductal adenocarcinoma Nat Rev Cancer 10 683-695
  • [5] Gutierrez RM(2011)Targeting Wnt signaling in colon cancer stem cells Clin Cancer Res 17 647-653
  • [6] Solis RV(2012)The Wnt/beta-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer J Cell Biochem 113 13-18
  • [7] JPt M(2013)WNT signalling pathways as therapeutic targets in cancer Nat Rev Cancer 13 11-26
  • [8] Wang SC(2016)The Wnt signaling pathway in cancer Crit Rev Oncol Hematol 99 141-149
  • [9] Hebrok M(2010)Orchids: a review of uses in traditional medicine, its phytochemistry and pharmacology J Med Plants Res 4 592-638
  • [10] de Sousa EM(2003)Advances in studies on pharmacology of plants from dendrobium Sw Chin Tradit Herb Drugs 34 19-22
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