Idiopathic scoliosis and concentrations of zinc, copper, and selenium in blood plasma

被引:0
作者
M. Dastych
J. Cienciala
机构
[1] Faculty Hospital Brno,Department of Clinical Biochemistry
[2] Faculty Hospital Brno,Orthopedic Clinic
来源
Biological Trace Element Research | 2002年 / 89卷
关键词
Idiopathic scoliosis; zinc; copper; selenium; blood plasma; SOD; GSH-Px;
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学科分类号
摘要
The concentration of zinc, copper, selenium, albumin, and ceruloplasmin in blood plasma and the activity of superoxide dismutase and glutathione peroxidase in erythrocytes were determined in a set of patients with idiopathic scoliosis (n=51). A significant decrease of selenium concentration (0.50±0.16 µmol/L) was found when compared with a control group (0.69±0.07 µmol/L) (p<0.01). The same levels of significance were found out for selenium levels corrected for albumin content. In a group of patients with a curvature over 45° indicated for a surgical correction, the average plasma concentrations of selenium were significantly lower (p<0.05) in comparison with a group of patients with a curvature below 45° treated conservatively.
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页码:105 / 110
页数:5
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共 75 条
[1]  
Renshaw T. S.(1993)Idiopathic scoliosis in children Curr. Opin. Pediatr. 5 407-412
[2]  
Veldhuizen A. G.(2000)The aetiology of idiopathic scoliosis: biomechanical and neuromuscular factors Eur. Spine J. 9 178-184
[3]  
Wever D. J.(1999)Adolescent idiopathic scoliosis Orthop, Clin. North Am. 30 353-365
[4]  
Webb P. J.(2000)Etiology of idiopathic scoliosis current trends in research J. Bone Joint Surg. Am. 82 1157-1168
[5]  
Roach J. W.(1980)Spinal deformites in Marfan’s syndrome Ital. J. Orthop. Traumatol. 6 19-40
[6]  
Lowe T. G.(1992)Orthopedic aspects of the Marfan phenotype Clin. Orthop. 277 251-261
[7]  
Edgar M.(1997)Evolving phenotype of Marfan’s syndrome Arch. Dis. Child. 76 41-46
[8]  
Margulies J. Y.(1980)Copper and the synthesis of elastin and collagen Ciba Found. Symp. 79 163-182
[9]  
Miller N. H.(1993)Copper deficiency alters collagen types and covalent cross-linking in swine myocardium and cardiac valves Am. J. Physiol. 264 H2154-H2161
[10]  
Raso V. J.(1982)Collagen levels in tissues from selenium deficient ducks Comp. Biochem. Physiol. A 72 383-389