Pragmatic consideration of recent randomized, placebo-controlled clinical trials for treatment of fibromyalgia

被引：0
|
作者：
Andrew J. Holman
机构：
[1] Pacific Rheumatology Research,
来源：
Current Pain and Headache Reports | 2008年 / 12卷
关键词：
Gabapentin; Pregabalin; Duloxetine; Pramipexole; Ropinirole;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A flurry of recent randomized, placebo-controlled trials assessing dissimilar pharmacotherapeutic treatment options for fibromyalgia (FM) have been presented in the past few years. This review evaluates these trials in light of recent pathophysiological concepts germane to FM, including mood disorders, autonomic dysregulation, altered sleep stage architecture, and the diagnostic tender point controversy. Studies with gabapentin, pregabalin, duloxetine, milnacipran, sodium oxybate, and pramipexole for treatment of FM are discussed.
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