Recent Developments in Psychopharmaceutical Approaches to Treating Female Sexual Interest and Arousal Disorder

被引：14

作者：

Both S. ^{[1
]}

机构：

[1] Department of Psychosomatic Gynecology and Sexology, Leiden University Medical Center, Albinusdreef 2, PO Box 9600, Leiden

来源：

Current Sexual Health Reports | 2017年 / 9卷 / 4期

关键词：

Pharmacological; Sexual arousal; Sexual desire; Sexual dysfunctions;

D O I：

10.1007/s11930-017-0124-3

中图分类号：

学科分类号：

摘要：

Purpose of Review: This review summarizes the recent literature and empirical studies on psychopharmacological approaches to treating female sexual interest/arousal disorder (FSIAD). Recent Findings: Several new drugs for FSIAD that are intended to increase sexual responsiveness by influencing central excitatory and inhibitory neuromodulatory processes are under development. Studies on flibanserin resulted in the first approved medication for the treatment of low sexual desire in premenopausal women. New drugs under development are testosterone combined with sildenafil or buspiron, bremelanotide, BP101, and nasal testosterone (TBS-2). Summary: Although pharmacological enhancement of sexual responsiveness may be potentially helpful in the treatment of FSIAD, the observed effects of flibanserin and other new drugs under development seem limited in terms of clinical significance. Given the multifactorial character of FSIAD, it may be important to integrate psychopharmacological treatment with sex therapy for optimal treatment efficacy. © 2017, The Author(s).

引用

页码：192 / 199

页数：7

共 41 条

[1]

Diagnostic and statistical manual of mental disorders: DSM-5, (2013)

[2]

Baumeister R.F., Catanese K.R., Vohs K.D., Is there a gender difference in strength of sex drive? Theoretical views, conceptual distinctions, and a review of relevant evidence, Personal Soc Psychol Rev, 5, pp. 242-273, (2001)

[3]

West S.L., D'Aloisio A.A., Agans R.P., Kalsbeek W.D., Borisov N.N., Thorp J.M., Prevalence of low sexual desire and hypoactive sexual desire disorder in a nationally representative sample of US women, Arch Intern Med, 168, 13, pp. 1441-1449, (2008)

[4]

Witting K., Santtila P., Varjonen M., Jern P., Johansson A., von der P.B., Sandnabba K., Female sexual dysfunction, sexual distress, and compatibility with partner, J Sex Med, 5, 11, pp. 2587-2599, (2008)

[5]

Shifren J.L., Monz B.U., Russo P.A., Segreti A., Johannes C.B., Sexual problems and distress in United States women: prevalence and correlates, Obstet Gynecol, 112, 5, pp. 970-978, (2008)

[6]

Toates F., An integrative theoretical framework for understanding sexual motivation, arousal, and behavior, J Sex Res, 46, 2-3, pp. 168-193, (2009)

[7]

Singer B., Toates F.M., Sexual motivation, J Sex Res, 23, pp. 481-501, (1987)

[8]

Whalen R.E., Sexual motivation, Psychol Rev, 73, pp. 151-163, (1966)

[9]

Barlow D.H., Causes of sexual dysfunction: the role of anxiety and cognitive interference, J Consult Clin Psychol, 54, 2, pp. 140-148, (1986)

[10]

Meston C.M., Buss D.M., Why humans have sex, Arch Sex Behav, 36, 4, pp. 477-507, (2007)

← 1 2 3 4 5 →