Characterization and cellular localization of PSG in rat testis

被引:0
作者
Le Ann Blomberg
Shao-Ming Wu
Ghenima Dirami
Martin Dym
Janice Y. Chou
Wai-Yee Chan
机构
[1] Georgetown University Medical Center,Department of Pediatrics
[2] Georgetown University Medical Center,Department of Cell Biology
[3] National Institute of Child Health and Human Development,Heritable Disorders Branch
[4] NIH,undefined
来源
Molecular and Cellular Biochemistry | 1997年 / 177卷
关键词
pregnancy-specific b1-glycoprotein; cDNA; rat; Sertoli; Leydig; myoid;
D O I
暂无
中图分类号
学科分类号
摘要
In order to establish the rat testis as a model system for studying the human pregnancy-specific b1-glycoprotein (PSG), expression and cellular distribution of PSG in rat testis were examined. Three partial PSG cDNAs, namely, rnCGM6, rnGCM7, and rnCGM8 were obtained when rat testis cDNA libraries were screened with a human placental PSG cDNA probe. Unlike the human PSGs, the rat PSGs show less nucleotide and amino acid sequence homology among family members. The rat PSGs also have multiple truncated leader sequences followed by immunoglobulin variable-like N domains while human PSGs have a single N domain.
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页码:229 / 237
页数:8
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