Post-kidney transplant soluble Klotho levels are determined by pretransplant soluble Klotho levels in both living donors and recipients

[1] Kuro-o M(1997)Mutation of the mouse klotho gene leads to a syndrome resembling ageing Nature 390 45-51

[2] Matsumura Y(2005)Suppression of aging in mice by the hormone Klotho Science 309 1829-1833

[3] Aizawa H(2006)Regulation of fibroblast growth factor-23 signaling by klotho J Biol Chem 281 6120-6123

[4] Kurosu H(2006)Klotho converts canonical FGF receptor into a specific receptor for FGF23 Nature 444 770-774

[5] Yamamoto M(2007)Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17 Proc Natl Acad Sci USA 104 19796-19801

[6] Clark JD(2009)Klotho is a substrate for alpha-, beta-, and gamma-secretase FEBS Lett 583 3221-3224

[7] Kurosu H(2004)Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane FEBS Lett 565 143-147

[8] Ogawa Y(2014)Identification of cleavage sites leading to the shed form of the anti-aging protein klotho Biochemistry 53 5579-5587

[9] Miyoshi M(2017)Effects of Klotho on fibrosis and cancer: a renal focus on mechanism and therapeutic strategies Adv Drug Deliv Rev 121 85-100

[10] Urakawa I(2012)Klotho as a potential biomarker and therapy for acute kidney injury Nat Rev Nephrol 8 423-429

[1] Kuro-o M(1997)Mutation of the mouse klotho gene leads to a syndrome resembling ageing Nature 390 45-51

[2] Matsumura Y(2005)Suppression of aging in mice by the hormone Klotho Science 309 1829-1833

[3] Aizawa H(2006)Regulation of fibroblast growth factor-23 signaling by klotho J Biol Chem 281 6120-6123

[4] Kurosu H(2006)Klotho converts canonical FGF receptor into a specific receptor for FGF23 Nature 444 770-774

[5] Yamamoto M(2007)Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17 Proc Natl Acad Sci USA 104 19796-19801

[6] Clark JD(2009)Klotho is a substrate for alpha-, beta-, and gamma-secretase FEBS Lett 583 3221-3224

[7] Kurosu H(2004)Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane FEBS Lett 565 143-147

[8] Ogawa Y(2014)Identification of cleavage sites leading to the shed form of the anti-aging protein klotho Biochemistry 53 5579-5587

[9] Miyoshi M(2017)Effects of Klotho on fibrosis and cancer: a renal focus on mechanism and therapeutic strategies Adv Drug Deliv Rev 121 85-100

[10] Urakawa I(2012)Klotho as a potential biomarker and therapy for acute kidney injury Nat Rev Nephrol 8 423-429