Overcoming doxorubicin resistance in triple-negative breast cancer using the class I-targeting HDAC inhibitor bocodepsin/OKI-179 to promote apoptosis

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作者
Stephen G. Smoots
Anna R. Schreiber
Marilyn M. Jackson
Stacey M. Bagby
Adrian T A. Dominguez
Evan D. Dus
Cameron A. Binns
Morgan MacBeth
Phaedra A. Whitty
Jennifer R. Diamond
Todd M. Pitts
机构
[1] University of Colorado Anschutz Medical Campus,Department of Medicine, Division of Medical Oncology
来源
Breast Cancer Research | / 26卷
关键词
Triple-negative breast cancer; Doxorubicin; Histone deacetylase inhibitor;
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  • [1] Almansour NM(2022)Triple-negative breast Cancer: a brief review about Epidemiology, Risk factors, signaling pathways, treatment and role of Artificial Intelligence Front Mol Biosci 9 836417-9
  • [2] Nitiss KC(2014)Twisting and ironing: doxorubicin cardiotoxicity by mitochondrial DNA damage Clin Cancer Res 20 4737-67
  • [3] Nitiss JL(2022)Event-free survival with Pembrolizumab in Early Triple-negative breast Cancer N Engl J Med 386 556-9
  • [4] Schmid P(2014)DNA torsion, and chromatin dynamics Biochim Biophys Acta 1845 84-23
  • [5] Cortes J(2019)Doxorubicin-Induced Cancer Cell Senescence shows a Time Delay Effect and is inhibited by Epithelial-Mesenchymal Transition (EMT) Med Sci Monit 25 3617-9
  • [6] Dent R(2019)Different sensitivities of senescent breast cancer cells to immune cell-mediated cytotoxicity Cancer Sci 110 2690-75
  • [7] Pusztai L(2022)Doxorubicin-induced senescence in normal fibroblasts promotes in vitro tumour cell growth and invasiveness: the role of Quercetin in modulating these processes Mech Ageing Dev 206 111689-61
  • [8] McArthur H(2021)Mechanisms of Cellular Senescence: cell cycle arrest and Senescence Associated Secretory phenotype Front Cell Dev Biol 9 645593-36
  • [9] Kummel S(2015)The fate of chemoresistance in triple negative breast cancer (TNBC) BBA Clin 3 257-29
  • [10] Yang F(2018)Cancer secretome and inflammation: the bright and the dark sides of NF-kappaB Semin Cell Dev Biol 78 51-70