Hepatoblastoma and prune belly syndrome: a potential association

被引：0
作者：
Brian Becknell
Priya Pais
Grace Onimoe
Hemalatha Rangarajan
Andrew L. Schwaderer
Kirk McHugh
Mark A. Ranalli
David S. Hains
机构：
[1] Ohio State University College of Medicine,Department of Pediatrics
[2] Medical College of Wisconsin,Division of Nephrology, Children’s Hospital of Wisconsin
[3] Nationwide Children’s Hospital,Division of Hematology and Oncology
[4] Medical College of Wisconsin,Division of Hematology and Oncology, Children’s Hospital of Wisconsin
[5] Nationwide Children’s Hospital,Division of Nephrology
[6] Center for Molecular and Human Genetics,undefined
[7] Research Institute at Nationwide Children’s Hospital,undefined
[8] Center for Clinical and Translational Research,undefined
[9] Center for Clinical and Translational Research,undefined
[10] Research Institute at Nationwide Children’s Hospital,undefined
来源：
Pediatric Nephrology | 2011年 / 26卷
关键词：
Prune belly syndrome; Hepatoblastoma; Malignancy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Prune belly syndrome (PBS) is a congenital anomaly characterized by the clinical triad of lax abdominal musculature, bilateral cryptorchidism, and abnormalities of the kidney and urinary tract. Previous reports of malignancy in patients with PBS have been limited to germ cell tumors. Hepatoblastoma (HBL) is the most common hepatic malignancy of childhood, affecting approximately 100 children each year in the USA. We describe a set of 4 pediatric patients with PBS and HBL. All individuals were born after 2002. These subjects lacked genetic, natal, or environmental factors known to confer risk of HBL. The occurrence of PBS and HBL in these patients constitutes a novel potential association.
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页码：1269 / 1273
页数：4
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