A retrospective epidemiological study of bacterial meningitis in an urban area in Belgium

被引:0
作者
Van Hoeck K.J. [1 ]
Mahieu L.M. [1 ]
Vaerenberg M.H. [2 ]
Van Acker K.J. [1 ]
机构
[1] Department of Paediatrics, Antwerp University Hospital, B-2650 Antwerp
[2] Antwerp Children's Hospital, Antwerp
关键词
Bacterial meningitis; Children; Epidemiology;
D O I
10.1007/s004310050602
中图分类号
学科分类号
摘要
In order to obtain epidemiological data on the incidence of bacterial meningitis (BM) before the systematic introduction of vaccination against Haemophilus influenzae type b, a retrospective study of 124 children with proven BM was performed in an urban area in Belgium. N. meningitidis was the most prevalent cause, followed by H. influenzae and S. pneumoniae. Over a period of 6 years the incidence of BM increased ten fold, mainly due to an increase in N. meningitidis. The median age of the children with BM was 17 months and 35% of those with H. influenzae were younger than 1 year. Significant risk factors for BM as a whole were: age under 1 year, male gender, non-Caucasian descent and winter time. These findings may have implications for future vaccination policy in Belgium. Conclusion: Future vaccination schemes in Belgium should take into account that N. meningitis was the prevalent cause of bacterial meningitis and that certain factors increase the risk for developing bacterial meningitis.
引用
收藏
页码:288 / 291
页数:3
相关论文
共 18 条
[1]  
Berger U., Sonntag H.G., Ulbrich C., Epidemiology of meningococcal infections in the Federal Republic of Germany, 1966-1984, Zentralbl Bakteriol Mikrobiol Hyg, 268, pp. 83-102, (1988)
[2]  
Black S.B., Shinefield H.R., Imunnisation with oligosaccharide conjugate Haemophilus influenzae type b vaccine on a large health maintenance organisation population: Extended follow up and impact on Haemophilus influenzae disease epidemiology, Pediatr Infect Dis J, 11, pp. 610-613, (1992)
[3]  
Bol P., Spanjaard L., Van Alphen L., Zanen H.C., Epidemiology of Haemophilus influenzae meningitis in patients more than 6 years of age, J Infect, 15, pp. 81-94, (1987)
[4]  
Claesson B.A., Epidemiology of invasive Haemophilus influeniae type b disease in Scandinavia, Vaccine, 11, (1993)
[5]  
De Morais J., Munford L.S., Rise J.N., Epidemic disease due to sero-group L Neisseria meningitidis in Sao Paulo, Brazil, J Infect Dis, 129, pp. 568-571, (1974)
[6]  
Feigin R.D., Central nervous system infections, Textbook of Pediatric Infectious Diseases, (1987)
[7]  
Fernandez-Crehuet-Navajas R., Martinez De La Eglesia J., Serrano Castillo A., Perula De Torres L., Clinical epidemiological assessment of bacterial meningitis in the province of Cordoba (1983-1989), Rev Sanid Hig Publica-Madrid, 65, pp. 127-135, (1991)
[8]  
Fortnum H.M., Davis A.C., Epidemiology of bacterial meningitis, Arch Dis Child, 68, pp. 763-767, (1993)
[9]  
Fox J.P., Epidemiology of infectious disease, Textbook of Pediatric Infectious Diseases, (1987)
[10]  
Grandi G., Malvestio G., Dotti G., Ciuti E., Fiorucci G.C., Bacterial meningitis. Study from 1970 to 1988 at the Regina Margherita Children's Hospital in Turin, G Batteriol Virol Immunol, 82, pp. 133-140, (1989)