Mouse retinal progenitor cell (RPC) cocultivation with retinal pigment epithelial cell culture affects features of RPC differentiation

被引：0
|
作者：
I. V. Kholodenko
A. A. Buzdin
R. V. Kholodenko
J. A. Baibikova
V. F. Sorokin
V. N. Yarygin
E. D. Sverdlov
机构：
[1] Russian Academy of Sciences,Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry
[2] Russian State Medical University,undefined
来源：
Biochemistry (Moscow) | 2006年 / 71卷
关键词：
retinal progenitor cell; retinal pigment epithelium; stem cell differentiation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We provide evidence that coculturing of retinal progenitor cells (RPC) with retinal pigment epithelial cells significantly biases the standard in vitro RPC differentiation patterns. In particular, in cocultivation experiments RPCs lost the ability to differentiate spontaneously and displayed ∼2.1–2.4-fold increase in immunoreactivity to the neural stem cell marker nestin and ∼1.6–1.7-fold increase in rod photoreceptor cell rhodopsin marker immunoreactivity. The data suggest the influence of the intercellular interaction networks on RPC differentiation.
引用
收藏
页码：767 / 774
页数：7
相关论文
共 50 条
  • [1] Mouse retinal progenitor cell (RPC) cocultivation with retinal pigment epithelial cell culture affects features of RPC differentiation
    Kholodenko, I. V.
    Buzdin, A. A.
    Kholodenko, R. V.
    Baibikova, J. A.
    Sorokin, V. F.
    Yarygin, V. N.
    Sverdlov, E. D.
    BIOCHEMISTRY-MOSCOW, 2006, 71 (07) : 767 - 774
  • [2] Transcriptional regulation of retinal pigment epithelial cell differentiation
    Vogel, JS
    Bullen, EC
    Howard, EW
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2004, 45 : U534 - U534
  • [3] Influence of a retinal pigment epithelial cell factor(s) on rat retinal progenitor cells
    Sheedlo, HJ
    Turner, JE
    DEVELOPMENTAL BRAIN RESEARCH, 1996, 93 (1-2): : 88 - 99
  • [4] Alginate as a Cell Culture Substrate for Growth and Differentiation of Human Retinal Pigment Epithelial Cells
    Heidari, Razeih
    Soheili, Zahra-Soheila
    Samiei, Shahram
    Ahmadieh, Hamid
    Davari, Maliheh
    Nazemroaya, Fatemeh
    Bagheri, Abouzar
    Deezagi, Abdolkhalegh
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 2015, 175 (05) : 2399 - 2412
  • [5] Alginate as a Cell Culture Substrate for Growth and Differentiation of Human Retinal Pigment Epithelial Cells
    Razeih Heidari
    Zahra-Soheila Soheili
    Shahram Samiei
    Hamid Ahmadieh
    Maliheh Davari
    Fatemeh Nazemroaya
    Abouzar Bagheri
    Abdolkhalegh Deezagi
    Applied Biochemistry and Biotechnology, 2015, 175 : 2399 - 2412
  • [6] The effects of amniotic membrane on retinal pigment epithelial cell differentiation
    Ohno-Matsui, K
    Ichinose, S
    Nakahama, K
    Yoshida, T
    Kojima, A
    Mochizuki, M
    Morita, I
    MOLECULAR VISION, 2005, 11 (01): : 1 - 10
  • [7] The effects of amniotic membrane on retinal pigment epithelial cell differentiation
    Ohno-Matsui, K
    Ichinose, S
    Yoshida, T
    Kojima, A
    Mochizuki, M
    Morita, I
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 2005, 46
  • [8] Retinal pigment epithelial cell culture in studies of drug toxicity
    Salminen, L
    Tahti, H
    Toimela, TA
    INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, 1996, 37 (03) : 1752 - 1752
  • [9] Light Filtering in a Retinal Pigment Epithelial Cell Culture Model
    Zhou, Jilin
    Sparrow, Janet R.
    OPTOMETRY AND VISION SCIENCE, 2011, 88 (06) : 759 - 765
  • [10] Neural cell differentiation from retinal pigment epithelial cells of the newt: An organ culture model for the urodele retinal regeneration
    Ikegami, Y
    Mitsuda, S
    Araki, M
    JOURNAL OF NEUROBIOLOGY, 2002, 50 (03): : 209 - 220
12345