Challenges to the Treatment and New Perspectives for the Eradication of Helicobacter pylori

被引：0
作者：
Priscila Baptistella Yazbek
Ariane Biolcati Trindade
Chung Man Chin
Jean Leandro dos Santos
机构：
[1] State University of São Paulo “Júlio de Mesquita Filho”,School of Pharmaceutical Science, Drugs and Medicines Department
来源：
Digestive Diseases and Sciences | 2015年 / 60卷
关键词：
Treatment; resistance; eradication; Gastric diseases;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Helicobacter pylori (H. pylori) is one of the leading causes of gastric diseases such as chronic gastritis, peptic ulcer, and gastric adenocarcinoma. The current treatment of H. pylori infection with antibiotics and proton pump inhibitors has several limitations, including poor adherence and intrinsic patient-related factors, drug resistance, and the absence of adequate treatments. This review summarizes the current therapeutic approaches to eradicating H. pylori, the difficulties associated with its treatment, and several new perspectives aimed at improving existing treatment strategies.
引用
收藏
页码：2901 / 2912
页数：11
相关论文
共 448 条
[1]  
Suerbaum S(2002) infection N Engl J Med 347 1175-1186
[2]  
Michetti P(2014)Exploring alternative treatments for World J Gastroenterol 20 1450-1469
[3]  
Ayala G(2010) infection Am Coll Surg 210 110-116
[4]  
Escobedo-Hinojosa WI(1983)“No acid, no ulcer”—100 years later: a review of the history of peptic ulcer disease Lancet 1 1273-1275
[5]  
Cruz-Herrera CF(1995)Unidentified curved bacilli on gastric epithelium in active chronic gastritis JAMA 272 65-69
[6]  
Romero I(2014) in peptic ulcer disease World J Gastroenterol 20 1438-1449
[7]  
Gustafson J(2014)A review of Dig Dis Sci 59 1698-1709
[8]  
Welling D(2011) diagnosis, treatment, and methods to detect eradication J Gastrointestin Liver Dis 20 299-304
[9]  
Warren JR(2013)Prevalence of Helicobacter 18 52-57
[10]  
Marshall BJ(2007) infection worldwide: a systematic review of studies with national coverage Helicobacter 12 1-3
12345678910