Genome-wide association study identifies eight loci associated with blood pressure

被引：0

作者：

Christopher Newton-Cheh

Toby Johnson

Vesela Gateva

Martin D Tobin

Murielle Bochud

Lachlan Coin

Samer S Najjar

Jing Hua Zhao

Simon C Heath

Susana Eyheramendy

Konstantinos Papadakis

Benjamin F Voight

Laura J Scott

Feng Zhang

Martin Farrall

Toshiko Tanaka

Chris Wallace

John C Chambers

Kay-Tee Khaw

Peter Nilsson

Pim van der Harst

Silvia Polidoro

Diederick E Grobbee

N Charlotte Onland-Moret

Michiel L Bots

Louise V Wain

Katherine S Elliott

Alexander Teumer

Jian'an Luan

Gavin Lucas

Johanna Kuusisto

Paul R Burton

David Hadley

Wendy L McArdle

Morris Brown

Anna Dominiczak

Stephen J Newhouse

Nilesh J Samani

John Webster

Eleftheria Zeggini

Jacques S Beckmann

Sven Bergmann

Noha Lim

Kijoung Song

Peter Vollenweider

Gerard Waeber

Dawn M Waterworth

Xin Yuan

Leif Groop

Marju Orho-Melander

机构：

[1] Center for Human Genetic Research,Department of Medical Genetics

[2] Massachusetts General Hospital,Department of Biostatistics and Center for Statistical Genetics

[3] Cardiovascular Research Center,Departments of Health Sciences and Genetics

[4] Massachusetts General Hospital,Department of Epidemiology and Public Health

[5] Program in Medical and Population Genetics,Division of Community Health Sciences

[6] Broad Institute of Harvard and Massachusetts Institute of Technology,Department of Twin Research and Genetic Epidemiology

[7] University of Lausanne,Department of Cardiovascular Medicine

[8] University Institute for Social and Preventative Medicine,Department of Public Health and Primary Care

[9] Centre Hospitalier Universitaire Vaudois (CHUV) and University of Lausanne,Department of Clinical Sciences

[10] Swiss Institute of Bioinformatics,Department of Cardiology

[11] University of Michigan,Department of Medical Genetics

[12] Adrian Building,DBG

[13] University of Leicester,Department of Medicine

[14] Imperial College London,Department of Social Medicine

[15] St. Mary's Campus,Department of Cardiovascular Science

[16] Norfolk Place,Genetics Division

[17] Laboratory of Cardiovascular Science,Department of Internal Medicine

[18] Intramural Research Program,Department of Clinical Sciences

[19] National Institute on Aging,Department of Genetics

[20] National Institutes of Health,Department of Clinical and Experimental Medicine

[21] MRC Epidemiology Unit,Department of Genetics

[22] Institute of Metabolic Science,Department of Epidemiology and Health Promotion

[23] Addenbrooke's Hospital,Cardiovascular Research Center and Cardiology Division

[24] Cambridge-Genetics of Energy Metabolism (GEM) Consortium,Departments of Medicine and Epidemiology

[25] Centre National de Génotypage,Department of Epidemiology

[26] Pontificia Universidad Católica de Chile,Department of Clinical Sciences/Obstetrics and Gynecology

[27] Facultad de Matemáticas,Department of Child and Adolescent Health

[28] Institute of Epidemiology,Division of Nephrology, Department of Medicine

[29] Helmholtz Zentrum München,Department of Epidemiology University Medical Center Groningen

[30] German Research Centre for Environmental Health,Department of Medicine Solna

[31] St. George's,Department of Medical Sciences

[32] University of London,Department of Epidemiology

[33] King's College London,Department of Internal Medicine B

[34] University of Oxford,Department of Public Health

[35] The Wellcome Trust Centre for Human Genetics,Department of Medicine and Department of Genetics

[36] Medstar Research Institute,Department of Biostatistics

[37] Clinical Research Branch,undefined

[38] National Institute on Aging,undefined

[39] Clinical Pharmacology,undefined

[40] William Harvey Research Institute,undefined

[41] Barts and The London School of Medicine and Dentistry,undefined

[42] Queen Mary University of London,undefined

[43] The Genome Centre,undefined

[44] William Harvey Research Institute,undefined

[45] Barts and The London School of Medicine and Dentistry,undefined

[46] Queen Mary University of London,undefined

[47] Juvenile Diabetes Research Foundation/Wellcome Trust Diabetes and Inflammation Laboratory,undefined

[48] Cambridge Institute for Medical Research University of Cambridge,undefined

[49] Wellcome Trust/MRC Building,undefined

[50] Addenbrooke's Hospital,undefined

来源：

Nature Genetics | 2009年 / 41卷

关键词：

D O I：

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中图分类号：

学科分类号：

摘要：

Christopher Newton-Cheh and colleagues report a genome-wide association study for blood pressure traits as part of the Global BPgen consortium. They report eight loci with replicated association to systolic and/or diastolic blood pressure, with each also showing association to hypertension.

引用

页码：666 / 676

页数：10

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