Wild type human TDP-43 potentiates ALS-linked mutant TDP-43 driven progressive motor and cortical neuron degeneration with pathological features of ALS

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作者
Jacqueline C Mitchell
Remy Constable
Eva So
Caroline Vance
Emma Scotter
Leanne Glover
Tibor Hortobagyi
Eveline S. Arnold
Shuo-Chien Ling
Melissa McAlonis
Sandrine Da Cruz
Magda Polymenidou
Lino Tessarolo
Don W Cleveland
Christopher E Shaw
机构
[1] Institute of Psychiatry,King’s Centre for Neurodegeneration Research, Kings College London, Department of Basic and Clinical Neurosciences
[2] Psychology and Neuroscience,Ludwig Institute for Cancer Research and Department of Molecular Medicine
[3] Centre for Ultrastructural Imaging,undefined
[4] Kings College London,undefined
[5] University of California at San Diego,undefined
[6] Mouse Cancer Genetics Program,undefined
[7] National Cancer Institute – Frederick,undefined
[8] Present address: Neurogenetics Branch,undefined
[9] NINDS,undefined
[10] National Institutes of Health,undefined
[11] Present address: Institute of Molecular Life Sciences,undefined
[12] University of Zurich,undefined
关键词
TDP-43; Amyotrophic lateral sclerosis; Mouse;
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