miR-190 promotes malignant transformation and progression of human urothelial cells through CDKN1B/p27 inhibition

被引:0
作者
Shirui Huang
Xiaohui Hua
Mengjiao Kuang
Junlan Zhu
Haiqi Mu
Zhongxian Tian
Xiaoqun Zheng
Qipeng Xie
机构
[1] The Second Affiliated Hospital & Yuying Children’s Hospital of Wenzhou Medical University,Department of Laboratory Medicine
[2] Anhui Medical University,Department of Occupational Health and Environmental Health, School of Public Health
[3] Wenzhou Medical University,School of Laboratory Medicine and Life Sciences
来源
Cancer Cell International | / 21卷
关键词
miR-190 ; Methylation ; Bladder epithelial cell transformation ;
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[1]  
Siegel RL(2018)Cancer statistics, 2018 CA Cancer J Clin 68 7-30
[2]  
Miller KD(2018)Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries CA Cancer J Clin 68 394-424
[3]  
Jemal A(2014)Intrinsic subtypes of high-grade bladder cancer reflect the hallmarks of breast cancer biology Proc Natl Acad Sci USA 111 3110-5
[4]  
Bray F(2014)Intrinsic basal and luminal subtypes of muscle-invasive bladder cancer Nat Rev Urol 11 400-10
[5]  
Ferlay J(2019)miR-221 targets QKI to enhance the tumorigenic capacity of human colorectal cancer stem cells Cancer Res 79 5151-8
[6]  
Soerjomataram I(2019)miR-190 enhances endocrine therapy sensitivity by regulating SOX9 expression in breast cancer J Exp Clin Cancer Res 38 22-20
[7]  
Siegel RL(2011)miR-190-mediated downregulation of PHLPP contributes to arsenic-induced Akt activation and carcinogenesis Toxicol Sci 123 411-1005
[8]  
Torre LA(2014)NF-κB1 p50 promotes p53 protein translation through miR-190 downregulation of PHLPP1 Oncogene 33 996-95
[9]  
Jemal A(2018)miR-190 promotes HCC proliferation and metastasis by targeting PHLPP1 Exp Cell Res 371 185-51
[10]  
Damrauer JS(2018)miR-190 suppresses breast cancer metastasis by regulation of TGF-beta-induced epithelial-mesenchymal transition Mol Cancer 17 70-605