Identification of the MHC class I B locus in cynomolgus monkeys

被引：2
作者：
Akihiko Uda
Kiyoshi Tanabayashi
Osamu Fujita
Akitoyo Hotta
Keiji Terao
Akio Yamada
机构：
[1] National Institute of Infectious Diseases,Department of Veterinary Science
[2] National Institute of Infectious Diseases,Tsukuba Primate Center for Medical Science
来源：
Immunogenetics | 2005年 / 57卷
关键词：
Cynomolgus; MHC; Allele;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
By determining the nucleotide sequences of more than 700 cDNA clones isolated from 16 cynomolgus monkeys, we identified 26 Mafa-B alleles. In addition, nine sequences with similarity to Mamu-I alleles were identified. Since multiple Mafa-B alleles were found in each individual, it was strongly suggested that the cynomolgus MHC class I B locus might be duplicated and that the Mafa-I locus was derived from the B locus by gene duplication, as in the case of the Mamu-I locus of rhesus monkeys.
引用
收藏
页码：189 / 197
页数：8
相关论文
共 138 条
  • [11] Alvarez M(2004) locus: exon 3 bears stop codons in all Cercopithecinae sequences Immunogenetics 56 142-154
  • [12] Castro MJ(2004)Definition of five new simian immunodeficiency virus cytotoxic T-lymphocyte epitopes and their restricting major histocompatibility complex class I molecules: evidence for an influence on disease progression Tissue Antigens 63 529-537
  • [13] Varela P(1993) allelic sequences incorporate distinct intragenic trans-specific segments Immunogenetics 38 141-145
  • [14] Gomez-Casado E(2002)Evolutionary relationships among the primate Immunogenetics 54 230-239
  • [15] Suarez B(1996) and Transplantation 61 989-996
  • [16] Recio MJ(1987) alleles Mol Biol Evol 4 406-425
  • [17] Vargas-Alarcon G(2001)Convergent evolution of major histocompatibility complex molecules in humans and New World monkeys J Immunol 166 3983-3993
  • [18] Morales P(2004)Pig-tailed macaques ( Immunogenetics 56 155-163
  • [19] Boyson JE(2000)) possess six MHC-E families that are conserved among macaque species: implication for their binding to natural killer receptor variants Immunogenetics 51 314-325
  • [20] McAdam SN(2000)-sequences from cynomolgus macaques ( J Immunol 164 1386-1398
12345678910