Identification of the MHC class I B locus in cynomolgus monkeys

被引：2
|
作者：
Akihiko Uda
Kiyoshi Tanabayashi
Osamu Fujita
Akitoyo Hotta
Keiji Terao
Akio Yamada
机构：
[1] National Institute of Infectious Diseases,Department of Veterinary Science
[2] National Institute of Infectious Diseases,Tsukuba Primate Center for Medical Science
来源：
Immunogenetics | 2005年 / 57卷
关键词：
Cynomolgus; MHC; Allele;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
By determining the nucleotide sequences of more than 700 cDNA clones isolated from 16 cynomolgus monkeys, we identified 26 Mafa-B alleles. In addition, nine sequences with similarity to Mamu-I alleles were identified. Since multiple Mafa-B alleles were found in each individual, it was strongly suggested that the cynomolgus MHC class I B locus might be duplicated and that the Mafa-I locus was derived from the B locus by gene duplication, as in the case of the Mamu-I locus of rhesus monkeys.
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页码：189 / 197
页数：8
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