Identification of the MHC class I B locus in cynomolgus monkeys

被引：2
作者：
Akihiko Uda
Kiyoshi Tanabayashi
Osamu Fujita
Akitoyo Hotta
Keiji Terao
Akio Yamada
机构：
[1] National Institute of Infectious Diseases,Department of Veterinary Science
[2] National Institute of Infectious Diseases,Tsukuba Primate Center for Medical Science
来源：
Immunogenetics | 2005年 / 57卷
关键词：
Cynomolgus; MHC; Allele;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
By determining the nucleotide sequences of more than 700 cDNA clones isolated from 16 cynomolgus monkeys, we identified 26 Mafa-B alleles. In addition, nine sequences with similarity to Mamu-I alleles were identified. Since multiple Mafa-B alleles were found in each individual, it was strongly suggested that the cynomolgus MHC class I B locus might be duplicated and that the Mafa-I locus was derived from the B locus by gene duplication, as in the case of the Mamu-I locus of rhesus monkeys.
引用
收藏
页码：189 / 197
页数：8
相关论文
共 138 条
  • [1] Alvarez M(1997)High polymorphism of Tissue Antigens 49 160-167
  • [2] Martinez-Laso J(1997) locus in non-human primates: alleles with identical exon 2 and 3 are found in two different species Immunogenetics 46 251-266
  • [3] Varela P(1995)Primate Immunogenetics 41 59-68
  • [4] Diaz-Campos N(1996) and J Immunol 157 5428-5437
  • [5] Gomez-Casado E(1996) alleles J Immunol 156 4656-4665
  • [6] Vargas-Alarcon G(1996)The Immunogenetics 43 327-336
  • [7] Garcia-Torre C(2000)locus in macaques is polymorphic and is conserved between macaques and humans J Virol 74 7400-7410
  • [8] Arnaiz-Villena A(1997)Identification of the rhesus monkey HLA-G ortholog. Mamu-G is a pseudogene Tissue Antigens 49 342-355
  • [9] Arnaiz-Villena A(1992)The MHC class I genes of the rhesus monkey. Different evolutionary histories of MHC class I and II genes in primates Immunogenetics 36 71-78
  • [10] Martinez-Laso J(2000)Allelic diversity at the primate Immunogenetics 51 169-178
12345678910