Skin prick testing in patients using beta-blockers: A retrospective analysis

被引：5

作者：

Fung I.N. ^{[1
]}

Kim H.L. ^{[1
,2
]}

机构：

[1] McMaster University, Hamilton, ON

[2] University of Western Ontario, London, ON

来源：

Allergy, Asthma & Clinical Immunology | / 6卷 / 1期

关键词：

Skin Testing; Skin Prick Testing; Cetirizine; Positive Skin Test; Atopic Subject;

D O I：

10.1186/1710-1492-6-2

中图分类号：

学科分类号：

摘要：

Rationale. The use of beta-blockers is a relative contraindication in allergen skin testing yet there is a paucity of literature on adverse events in this circumstance. We examined a population of skin tested patients on beta-blockers to look for any adverse effects. Methods. Charts from 2004-2008 in a single allergy clinic were reviewed for any patients taking a beta-blocker when skin tested. Data was examined for skin test reactivity, type of skin test, concomitant asthma diagnosis, allergens tested, and adverse events. Results: One hundred and ninety-one patients were taking beta-blockers when skin testing occurred. Seventy-two patients had positive skin tests. No tests resulted in an adverse event. Conclusions: This data demonstrates the relative safety of administrating of skin prick tests to patients on beta-blocker treatment. Larger prospective studies are needed to substantiate the findings of this study. © 2010 Fung and Kim; licensee BioMed Central Ltd.

引用

共 35 条

[1]

Foody J.M., Farrell M.H., Krumholz H.M., β-blocker therapy in heart failure: Scientific review, Journal of the American Medical Association, 287, 7, pp. 883-889, (2002)

[2]

Yusuf S., Peto R., Lewis J., Beta blockade during and after myocardial infarction: An overview of the randomized trials, Progress in Cardiovascular Diseases, 27, 5, pp. 335-371, (1985)

[3]

Freemantle N., Cleland J., Young P., Mason J., Harrison J., β blockade after myocardial infarction: Systematic review and meta regression analysis, British Medical Journal, 318, 7200, pp. 1730-1737, (1999)

[4]

Momeni M., Brui B., Baele P., Matta A., Anaphylactic shock in a beta-blocked child: Usefulness of isoproterenol, Paediatric Anaesthesia, 17, 9, pp. 897-899, (2007)

[5]

Jacobs R.L., Rake Jr. G.W., Fournier D.C., Potentiated anaphylaxis in patients with drug-induced beta-adrenergic blockade, Journal of Allergy and Clinical Immunology, 68, 2, pp. 125-127, (1981)

[6]

Newman B.R., Schultz L.K., Epinephrine-resistant anaphylaxis in a patient taking propranolol hydrochloride, Annals of Allergy, 47, 1, pp. 35-37, (1981)

[7]

Hannaway P.J., Hopper G.D.K., Severe anaphylaxis and drug-induced beta-blockade, New England Journal of Medicine, 308, 25, (1983)

[8]

Awai L.E., Mekori Y.A., Insect sting anaphylaxis and beta-adrenergic blockade: A relative contraindication, Annals of Allergy, 53, 1, pp. 48-49, (1984)

[9]

Ingall M., Goldman G., Page L.B., Beta-Blockade in Stinging Insect Anaphylaxis, JAMA, 251, 11, (1984)

[10]

Berkelman R.L., Finton R.J., Elsea W.R., Beta-adrenergic antagonists and fatal anaphylactic reactions to oral penicillin, Annals of Internal Medicine, 104, 1, (1986)

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