Regenerative medicine using stem cells from human exfoliated deciduous teeth (SHED): a promising new treatment in pediatric surgery

被引：0
|
作者：
Tomoaki Taguchi
Yusuke Yanagi
Koichiro Yoshimaru
Xiu-Ying Zhang
Toshiharu Matsuura
Koichi Nakayama
Eiji Kobayashi
Haruyoshi Yamaza
Kazuaki Nonaka
Shouichi Ohga
Takayoshi Yamaza
机构：
[1] Kyushu University,Department of Pediatric Surgery, Graduate School of Medical Science
[2] Saga University,Department of Regenerative Medicine and Biomedical Engineering, Faculty of Medicine
[3] Keio University School of Medicine,Department of Organ Fabrication
[4] Kyushu University,Department of Pediatric Dentistry, Graduate School of Dental Science
[5] Kyushu University,Department of Pediatrics, Graduate School of Medical Sciences
[6] Kyushu University,Department of Molecular Cell Biology and Oral Anatomy, Graduate School of Dental Science
来源：
Surgery Today | 2019年 / 49卷
关键词：
Mesenchymal stem cell; Dental pulp; Primary teeth; Biliary atresia; Diaphragm;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Stem cells from human exfoliated deciduous teeth (SHEDs), being a type of mesenchymal stem cell, are an ideal cell source for regenerative medicine. They have minimal risk of oncogenesis, high proliferative capacity, high multipotency, and immunosuppressive ability. Stem cell transplantation using SHED has been found to have an anti-fibrotic effect on liver fibrosis in mice. SHED transplantation and the bio 3D printer, which can create scaffold-free 3-D images of the liver and diaphragm, provide a new innovative treatment modality for intractable pediatric surgical diseases such as biliary atresia and diaphragmatic hernia.
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页码：316 / 322
页数：6
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