The Safety, Tolerability, and Efficacy of Once-Daily Memantine (28 mg): A Multinational, Randomized, Double-Blind, Placebo-Controlled Trial in Patients with Moderate-to-Severe Alzheimer’s Disease Taking Cholinesterase Inhibitors

被引：0
|
作者：
George T. Grossberg
Facundo Manes
Ricardo F. Allegri
Luis Miguel Gutiérrez-Robledo
Sergio Gloger
Lei Xie
X. Daniel Jia
Vojislav Pejović
Michael L. Miller
James L. Perhach
Stephen M. Graham
机构：
[1] Saint Louis University School of Medicine,Department of Neurology and Psychiatry
[2] Instituto de Neurología Cognitiva (INECO),undefined
[3] Instituto de Investigaciones Neurológicas Raúl Carrea (FLENI),undefined
[4] Instituto de Geriatría,undefined
[5] Institutos Nacionales de Salud de México,undefined
[6] PsicoMedica Clinical and Research Group,undefined
[7] Forest Research Institute,undefined
[8] Prescott Medical Communications Group,undefined
来源：
CNS Drugs | 2013年 / 27卷
关键词：
Memantine; Cholinesterase Inhibitor; Semantic Fluency; Verbal Fluency Test; Severe Impairment Battery;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：469 / 478
页数：9
相关论文
共 50 条
  • [21] Efficacy and safety of once-daily inhaled ciclesonide in adults with mild to moderate asthma: A double-blind, placebo-controlled study
    Adachi, Mitsuru
    Ishihara, Kyosuke
    Inoue, Hiroshi
    Kudo, Koichiro
    Takahashi, Kiyoshi
    Morita, Yutaka
    Masuda, Ken-Ichi
    Takada, Yoshinori
    Kato, Ryuichi
    Miyamoto, Terumasa
    RESPIROLOGY, 2007, 12 (04) : 566 - 572
  • [22] Memantine treatment for Japanese patients with moderate to severe Alzheimer's disease: a meta-analysis of double-blind, randomized, placebo-controlled trials
    Kishi, Taro
    Matsunaga, Shinji
    Iwata, Nakao
    NEUROPSYCHIATRIC DISEASE AND TREATMENT, 2018, 14 : 2915 - 2922
  • [23] Efficacy and safety of vunakizumab in moderate-to-severe chronic plaque psoriasis: A randomized, double-blind, placebo-controlled phase 3 trial
    Yan, Kexiang
    Li, Fuqiu
    Bi, Xiaodong
    Han, Ling
    Zhang, Zhenghua
    Chen, Rixin
    Li, Yuye
    Zhang, Litao
    Wang, Xiaohua
    Li, Linfeng
    Lu, Jianyun
    Xu, Ai'e
    Yang, Sen
    Lu, Yan
    Sun, Jianfang
    Li, Zhiming
    Zhu, Xiaohong
    Jiang, Meiying
    Zhang, Siping
    Wang, Wenqing
    Li, Yanling
    Meng, Zudong
    Li, Hongyi
    Mou, Kuanhou
    Han, Xiuping
    Li, Shanshan
    Chen, Aijun
    Li, Xin
    Liu, Donghua
    Zhang, Chunlei
    Ji, Chao
    Wang, Yu
    Cheng, Hao
    Cui, Xiaojing
    Yao, Xiaoyan
    Bai, Xiaoyan
    Dong, Guangchao
    Xu, Jinhua
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2025, 92 (01) : 92 - 99
  • [24] Liraglutide once daily versus placebo in Parkinson's disease: a randomized, double-blind, placebo-controlled trial
    Wu, T.
    Bresee, C.
    Wertheimer, J.
    Hogg, E.
    Malatt, C.
    Tan, E.
    Pomeroy, H.
    Obialisi, G.
    Tagliati, M.
    MOVEMENT DISORDERS, 2022, 37 : S359 - S360
  • [25] Efficacy and Safety of Once-Daily Dosing of Udenafil in the Treatment of Erectile Dysfunction: Results of a Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial
    Zhao, Chen
    Kim, Sae Woong
    Yang, Dae Yul
    Kim, Je Jong
    Park, Nam Cheol
    Lee, Sung Won
    Paick, Jae Seung
    Ahn, Tai Young
    Min, Kweon Sik
    Park, Kwangsung
    Park, Jong Kwan
    EUROPEAN UROLOGY, 2011, 60 (02) : 380 - 387
  • [26] Efficacy and tolerability of once-daily extended release quetiapine fumarate in acute schizophrenia: A randomized, double-blind, placebo-controlled study
    Kahn, Rene S.
    Schulz, S. Charles
    Palazov, Veselin D.
    Reyes, Efren B.
    Brecher, Martin
    Svensson, Ola
    Andersson, Henrik M.
    Meulien, Didier
    JOURNAL OF CLINICAL PSYCHIATRY, 2007, 68 (06) : 832 - 842
  • [27] Efficacy and safety of GV1001 in patients with moderate-to-severe Alzheimer’s disease already receiving donepezil: a phase 2 randomized, double-blind, placebo-controlled, multicenter clinical trial
    Seong-Ho Koh
    Hyuk Sung Kwon
    Seong Hye Choi
    Jee Hyang Jeong
    Hae Ri Na
    Chan Nyoung Lee
    YoungSoon Yang
    Ae Young Lee
    Jae-Hong Lee
    Kyung Won Park
    Hyun Jeong Han
    Byeong C. Kim
    Jin Se Park
    Jee-Young Lee
    Sangjae Kim
    Kyu-Yong Lee
    Alzheimer's Research & Therapy, 13
  • [28] Efficacy and safety of GV1001 in patients with moderate-to-severe Alzheimer's disease already receiving donepezil: a phase 2 randomized, double-blind, placebo-controlled, multicenter clinical trial
    Koh, Seong-Ho
    Kwon, Hyuk Sung
    Choi, Seong Hye
    Jeong, Jee Hyang
    Na, Hae Ri
    Lee, Chan Nyoung
    Yang, YoungSoon
    Lee, Ae Young
    Lee, Jae-Hong
    Park, Kyung Won
    Han, Hyun Jeong
    Kim, Byeong C.
    Park, Jin Se
    Lee, Jee-Young
    Kim, Sangjae
    Lee, Kyu-Yong
    ALZHEIMERS RESEARCH & THERAPY, 2021, 13 (01)
  • [29] A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety, Tolerability, and Efficacy of AMG 827 in Subjects With Moderate to Severe Crohn's Disease
    Targan, Stephan R.
    Feagan, Brian G.
    Vermeire, Severine
    Panaccione, Remo
    Melmed, Gil Y.
    Blosch, Consuelo
    Newmark, Richard
    Zhang, Nan
    Chon, Yun
    Lin, Shao-Lee
    Klekotka, Paul
    GASTROENTEROLOGY, 2012, 143 (03) : E26 - E26
  • [30] Efficacy and safety of desloratadine 5 mg once daily in the treatment of chronic idiopathic urticaria: A double-blind, randomized, placebo-controlled trial
    Monroe, E
    Finn, A
    Patel, P
    Guerrero, R
    Ratner, P
    Bernstein, D
    JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2003, 48 (04) : 535 - 541
12345