How does PKMζ maintain long-term memory?

被引：0

作者：

Todd C. Sacktor

机构：

[1] Todd C. Sacktor is at The Robert F. Furchgott Center of Neural and Behavioural Science,Departments of Physiology and Pharmacology and of Neurology

[2] State University of New York (SUNY) Downstate Medical Center,undefined

[3] 450 Clarkson Avenue,undefined

[4] Brooklyn,undefined

[5] New York 11203,undefined

[6] USA. tsacktor@downstate.edu,undefined

来源：

Nature Reviews Neuroscience | 2011年 / 12卷

关键词：

D O I：

暂无

中图分类号：

学科分类号：

摘要：

In this Progress article, Sacktor highlights the key role of protein kinase Mζ (PKMζ) — the constitutively active protein kinase C isoform — in perpetuating the synaptic events underlying long-term memory, and proposes a model of 'synaptic autotagging' by which this enzyme maintains its localization at the synapse.

引用

页码：9 / 15

页数：6

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