How does PKMζ maintain long-term memory?

被引：0
|
作者：
Todd C. Sacktor
机构：
[1] Todd C. Sacktor is at The Robert F. Furchgott Center of Neural and Behavioural Science,Departments of Physiology and Pharmacology and of Neurology
[2] State University of New York (SUNY) Downstate Medical Center,undefined
[3] 450 Clarkson Avenue,undefined
[4] Brooklyn,undefined
[5] New York 11203,undefined
[6] USA. tsacktor@downstate.edu,undefined
来源：
Nature Reviews Neuroscience | 2011年 / 12卷
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摘要：
In this Progress article, Sacktor highlights the key role of protein kinase Mζ (PKMζ) — the constitutively active protein kinase C isoform — in perpetuating the synaptic events underlying long-term memory, and proposes a model of 'synaptic autotagging' by which this enzyme maintains its localization at the synapse.
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页码：9 / 15
页数：6
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