18F-labeling techniques for positron emission tomography

被引：0
作者：
Ying Li
机构：
[1] Nanjing University of Information Science & Technology,Jiangsu Key Laboratory of Atmospheric Environment Monitoring & Pollution Control, Chemistry Department, School of Environmental Science & Engineering
来源：
Science China Chemistry | 2013年 / 56卷
关键词：
molecular imaging; positron emission tomography; F-fluorine/fluoride; specific activity; radiochemical yield;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Much research effort has been made to understand various biological processes at levels of molecules using molecular imaging techniques. Because of great sensitivity, high resolution, and rapid detection, positron emission tomography (PET) imaging is becoming one of the most used imaging techniques for medical diagnose and pre-clinical studies. Here we provide a review on molecular imaging and PET imaging. An introduction is also provided on 18F-fluorine labeling techniques for the preparation of PET imaging probes. A summary and comparison of currently available 18F-fluorine labeling methods is provided. The perspectives for 18F-fluorine labeling techniques are also given.
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页码：1682 / 1692
页数：10
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  • [1] Herschman HR(2003)Molecular imaging: Looking at problems, seeing solutions Science 302 605-608
  • [2] Doubrovin M(2004)Multimodality Bioconjugate Chem 15 1376-1388
  • [3] Serganova I(2008) molecular-genetic imaging Nat Rev Drug Discovery 7 591-607
  • [4] Mayer-Kuckuk P(2013)Molecular imaging in drug development Br J Pharmacol 169 719-735
  • [5] Ponomarev V(2012)Non-invasive molecular imaging for preclinical cancer therapeutic development Eur Rev Med Pharmacol Sci 16 1925-1933
  • [6] Blasberg RG(2013)From molecular imaging in preclinical/clinical oncology to theranostic applications in targeted tumor therapy J Nucl Med 54 1-4
  • [7] Willmann JK(2006)Recent advances in the molecular imaging of programmed cell death: Part II-Non-probe-based MRI, ultrasound, and optical clinical imaging techniques Annu Rev Med 57 99-118
  • [8] van Bruggen N(2013)Molecular imaging in the development of cancer therapeutics Sci China Chem 56 1247-1252
  • [9] Dinkelborg LM(2013)Biocompatible organic dots with aggregation-induced emission for Sci China Phys Mech Astron 56 506-513
  • [10] Gambhir SS(2013) and Sci China Phys Mech Astron 56 1310-1316
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