Topographic and tomographic parameters alone are often not sufficient for early detection of corneal changes. Pathological alterations in the microstructure of the cornea occur before changes in topography and tomography can be detected. Biomechanical parameters show a strong correlation with microscopic structural changes. The aim of the study was to gain information about the microscopic structure and consistency of the cornea by measuring biomechanical parameters. The deformation behavior of the cornea was analyzed with the Dynamic Scheimpflug Analyzer (Corvis ST; OCULUS, Wetzlar, Germany). Deformation parameters and biomechanical indices were derived from the deformation response of the cornea. Deformation parameters and indices in keratoconus patients differ significantly from healthy subjects. Alterations of the cornea can be detected before topographic and tomographic changes occur. The repeatability and reproducibility of relevant deformation parameters is good to very good. In glaucoma patients a modified deformation behavior of the cornea can be observed, which might be related to structural changes. The Corvis ST allows a reliable characterization of the tissue structure and consistency of the cornea.
机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Wang, Jingyi
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Li, Ying
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机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Li, Ying
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Jin, Yumei
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机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Jin, Yumei
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Yang, Xue
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机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Yang, Xue
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Zhao, Chan
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机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Zhao, Chan
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Long, Qin
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Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R ChinaChinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
机构:
Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R ChinaSun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China
Wang, Wei
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Du, Shaolin
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Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R ChinaSun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China
Du, Shaolin
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Zhang, Xiulan
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Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R ChinaSun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China
机构:
Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Ye, Cong
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Yu, Marco
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机构:
Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Hang Seng Management Coll, Dept Math & Stat, Hong Kong, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Yu, Marco
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Lai, Gilda
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Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Lai, Gilda
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Jhanji, Vishal
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机构:
Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Univ Melbourne, Ctr Eye Res Australia, Melbourne, Vic 3010, AustraliaChinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Wang, Jingyi
;
Li, Ying
论文数: 0引用数: 0
h-index: 0
机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Li, Ying
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Jin, Yumei
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机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Jin, Yumei
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Yang, Xue
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机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Yang, Xue
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Zhao, Chan
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h-index: 0
机构:Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
Zhao, Chan
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Long, Qin
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机构:
Chinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R ChinaChinese Acad Med Sci, Peking Union Med Coll Hosp, Dept Ophthalmol, Beijing 100730, Peoples R China
机构:
Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R ChinaSun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China
Wang, Wei
;
Du, Shaolin
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h-index: 0
机构:
Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R ChinaSun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China
Du, Shaolin
;
Zhang, Xiulan
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h-index: 0
机构:
Sun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R ChinaSun Yat Sen Univ, State Key Lab Ophthalmol, Zhongshan Ophthalm Ctr, Guangzhou 510060, Guangdong, Peoples R China
机构:
Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Ye, Cong
;
Yu, Marco
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Hang Seng Management Coll, Dept Math & Stat, Hong Kong, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Yu, Marco
;
Lai, Gilda
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R ChinaChinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Lai, Gilda
;
Jhanji, Vishal
论文数: 0引用数: 0
h-index: 0
机构:
Chinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China
Univ Melbourne, Ctr Eye Res Australia, Melbourne, Vic 3010, AustraliaChinese Univ Hong Kong, Dept Ophthalmol & Visual Sci, Hong Kong, Hong Kong, Peoples R China