Cyclocondensation of 2-amino-1,3,4-thiadiazoles with β-sulfonylvinyl-trifluoromethyldiols

被引：0

作者：

Krasovsky A.L. ^{[1
]}

Moiseev A.M. ^{[1
]}

Nenajdenko V.G. ^{[1
]}

Balenkova E.S. ^{[1
]}

机构：

[1] M. V. Lomonosov Moscow State Univ.

来源：

Chemistry of Heterocyclic Compounds | 2002年 / 38卷 / 02期

基金：

俄罗斯基础研究基金会;

关键词：

β-sulfonyl-vinyltrifluoromethyldiols; 2-amino-1,3,4-thiadiazoles; 6,7-dihydro-5H-[1,3,4]thiadiazolo[3,2-a] pyrimidines; Cyclocondensation;

D O I：

10.1023/A:1015303712382

中图分类号：

学科分类号：

摘要：

A series of CF3-containing 6,7-dihydro-5H-[1,3,4] thiadiazolo[3,2-a]pyrimidin-7-ols was obtained by the interaction of 2-amino-1,3,4-thiadiazoles with β-sulfonylvinyltrifluoromethyldiols and their stereochemistry was established. The structure of 5-(phenylsulfonyl)-7-(trifluoromethyl)-6,7-dihydro- 5H-[1,3,4]thiadiazolo[3,2-a]pyrimidin-7-ol was confirmed by X-ray crystallography.

引用

页码：231 / 237

页数：6

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