Single-nucleus RNA sequencing of human pancreatic islets identifies novel gene sets and distinguishes β-cell subpopulations with dynamic transcriptome profiles

被引:0
作者
Randy B. Kang
Yansui Li
Carolina Rosselot
Tuo Zhang
Mustafa Siddiq
Prashant Rajbhandari
Andrew F. Stewart
Donald K. Scott
Adolfo Garcia-Ocana
Geming Lu
机构
[1] Diabetes,Present address: Department of Molecular and Cellular Endocrinology
[2] Obesity and Metabolism Institute,Department of Pharmacological Sciences and Institute for Systems Biomedicine
[3] and Division of Endocrinology,undefined
[4] Diabetes and Bone Diseases,undefined
[5] Icahn School of Medicine at Mount Sinai,undefined
[6] Arthur Riggs Diabetes and Metabolism Research Institute,undefined
[7] Beckman Research Institute,undefined
[8] City of Hope,undefined
[9] Genomics Resources Core Facility,undefined
[10] Weill Cornell Medicine,undefined
[11] Mindich Child Health and Development Institute,undefined
[12] Icahn School of Medicine at Mount Sinai,undefined
[13] Icahn School of Medicine at Mount Sinai,undefined
来源
Genome Medicine | / 15卷
关键词
Diabetes; Human islet; Human pancreatic beta cell; Single-cell RNA sequencing; Single-nucleus RNA sequencing; Human islet graft;
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