In renal cell carcinoma the PTEN splice variant PTEN-Δ shows similar function as the tumor suppressor PTEN itself

[1] Steck PA(1997)Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers Nat Genet 15 356-362

[2] Pershouse MA(2009)PTEN and the PI3-kinase pathway in cancer Annu Rev Pathol 4 127-150

[3] Jasser SA(2012)The functions and regulation of the PTEN tumour suppressor Nat Rev Mol Cell Biol 13 283-296

[4] Yung WK(1997)P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase Proc Natl Acad Sci U S A 94 9052-9057

[5] Lin H(2002)Loss of tumor suppressor protein PTEN during renal carcinogenesis Int J Cancer 99 53-57

[6] Ligon AH(1997)PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer Science 275 1943-1947

[7] Langford LA(2015)Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas Mol Cancer 14 93-13378

[8] Baumgard ML(1998)The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3, 4, 5-trisphosphate J Biol Chem 273 13375-125

[9] Hattier T(2007)PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration Curr Biol 17 115-831

[10] Davis T(2011)Migration of renal tumor cells depends on dephosphorylation of Shc by PTEN Int J Oncol 38 823-242

[1] Steck PA(1997)Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers Nat Genet 15 356-362

[2] Pershouse MA(2009)PTEN and the PI3-kinase pathway in cancer Annu Rev Pathol 4 127-150

[3] Jasser SA(2012)The functions and regulation of the PTEN tumour suppressor Nat Rev Mol Cell Biol 13 283-296

[4] Yung WK(1997)P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase Proc Natl Acad Sci U S A 94 9052-9057

[5] Lin H(2002)Loss of tumor suppressor protein PTEN during renal carcinogenesis Int J Cancer 99 53-57

[6] Ligon AH(1997)PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer Science 275 1943-1947

[7] Langford LA(2015)Co-deleting Pten with Rb in retinal progenitor cells in mice results in fully penetrant bilateral retinoblastomas Mol Cancer 14 93-13378

[8] Baumgard ML(1998)The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3, 4, 5-trisphosphate J Biol Chem 273 13375-125

[9] Hattier T(2007)PtdIns(3,4,5)P(3)-dependent and -independent roles for PTEN in the control of cell migration Curr Biol 17 115-831

[10] Davis T(2011)Migration of renal tumor cells depends on dephosphorylation of Shc by PTEN Int J Oncol 38 823-242