Electronic Data Capture (EDC) using cellular technology: Implications for clinical trials and practice, and preliminary experience with the m-Womac ® Index in hip and knee OA patients

被引：11

作者：

Bellamy N. ^{[1
]}

Wilson C. ^{[1
]}

Hendrikz J. ^{[1
]}

Patel B. ^{[2
]}

Dennison S. ^{[2
]}

机构：

[1] Centre of National Research on Disability and Rehabilitation Medicine (CONROD), University of Queensland, Brisbane

[2] Exco InTouch, Harlow

来源：

Inflammopharmacology | 2009年 / 17卷 / 2期

关键词：

EDC; Health status measurement; Mobile phone; Osteoarthritis; WOMAC[!sup]®[!/sup;

D O I：

10.1007/s10787-008-8045-4

中图分类号：

学科分类号：

摘要：

Aim: The capture, analysis and utilisation of health status information are attended by logistic considerations and interpretation challenges. We report a preliminary evaluation of cellular technology in capturing WOMAC® NRS 3.1 Index data. Methods:: A Java midlet for delivering the WOMAC ® NRS3.1 Index on Nokia-6300, Motorola-V3 and Samsung-A711 mobile phones was developed by Exco InTouch. Following task orientation, patients completed the paper-based WOMAC® (p-WOMAC®) questionnaire, and then the three mobile phonebased WOMAC® (m-WOMAC®) applications, in random order. Results:: All 12 patients (age range = 55-82 years) successfully completed the m-WOMAC ® Index on each of the three phones, and all were found acceptable by patients. With respect to m-WOMAC® mean overall rank score, no significant difference was found between the 3 phones (Friedman's chi square (2 df) = 2.2, p = 0.34) however, Motorola V3 was favoured with the best mean rank. Pearson correlation between the average p-WOMAC® and average m-WOMAC® score was 0.996. Conclusions:: Patient reported ratings indicated the m-WOMAC® application performed well on all three phones. EDC provides unique opportunities for using quantitative measurement in both clinical practice and research. © 2009 Birkhäuser Verlag, Basel.

引用

页码：93 / 99

页数：6

共 54 条

[31]

Dougados M., LeClaire P., van der Heijde D., Bloch D.A., Bellamy N., Altman R.D., Special Article: Response criteria for clinical trials on osteoarthritis of the knee and hip: A report of the Osteoarthritis Research Society International Standing Committee for Clinical Trials Response Criteria Initiative, OA & Cart, 8, 6, pp. 395-403, (2000)

[32]

Dworkin R., Turk D., Farrar J., Haythornthwaite J.A., Jensen M.P., Katz N.P., Kerns R.D., Stucki G., Allen R.R., Bellamy N., Et al., Core outcome measures for chronic pain clinical trials: IMMPACT recommendations, Pain, 113, 1-2, pp. 9-19, (2005)

[33]

Ehrich E.W., Davies G.M., Watson D.J., Bolognese J.A., Seidenberg B.C., Bellamy N., Minimal perceptible clinical Improvement with the Western Ontario and McMaster Universities osteoarthritis index questionnaire and global assessments in patients with osteoarthritis, J. Rheumatol, 27, 11, pp. 2635-2641, (2000)

[34]

Points to Consider on Clinical Investigation of Medicinal Products used in the Treatment of Osteoarthritis, pp. 1-6, (1998)

[35]

Kellgren J.H., Lawrence J.S., Radiological assessment of osteoarthrosis, Ann Rheum Dis, 16, pp. 494-502, (1957)

[36]

Kvien T.K., Mowinckel P., Heiberg T., Dammann K.L., Dale O., Aanerud G.J., Alme T.N., Uhlig T., Performance of health status measures with a pen based personal digital assistant, Ann Rheum Dis, 64, 10, pp. 1480-1484, (2005)

[37]

Lybrand S., Bellamy N., Impact of OARSI-OMERACT recommendations for outcome measurement on clinical practice: A 5 year reassessment, NZA-ARA Combined Scientific Conference, (2002)

[38]

Palmblad M., Tiplady B., Electronic diaries and questionnaires: Designing user interfaces that are easy for all patients to use, Qual Life Res, 13, pp. 1199-1207, (2004)

[39]

(2007)

[40]

Pham T., van der Heijde D., Altman R.D., Anderson J.J., Bellamy N., Hochberg M., Simon L., Strand V., Woodworth T., Dougados M., OMERACT-OARSI Initiative: Osteoarthritis Research Society International set of responder criteria for osteoarthritis clinical trials revisited, OA & Cart, 12, pp. 389-399, (2004)

← 1 2 3 4 5 6 →