Patient and provider perspectives on polygenic risk scores: implications for clinical reporting and utilization

[1] Khera AV(2018)Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations Nat Genet 50 1219-1224

[2] Chaffin M(2017)The WISDOM Study: breaking the deadlock in the breast cancer screening debate Npj Breast Cancer 3 1-7

[3] Aragam KG(2019)Clinical use of current polygenic risk scores may exacerbate health disparities Nat Genet 51 584-1884

[4] Haas ME(2021)Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps Nat Med 27 1876-1188

[5] Roselli C(2022)How Communicating Polygenic and Clinical Risk for Atherosclerotic Cardiovascular Disease Impacts Health Behavior: an Observational Follow-up Study Circ Genomic Precis Med 0 CIRCGEN.121.003459-424

[6] Choi SH(2016)Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates Circulation. 133 1181-87

[7] Esserman LJ(2015)Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology Genet Med 17 405-280

[8] Martin AR(2021)Design and user experience testing of a polygenic score report: a qualitative study of prospective users BMC Med Genet 14 238-1088

[9] Kanai M(2022)Why do people seek out polygenic risk scores for complex disorders, and how do they understand and react to results? Eur J Hum Genet 30 81-618

[10] Kamatani Y(2012)Communicating risk BMJ. 344 270-482

[1] Khera AV(2018)Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations Nat Genet 50 1219-1224

[2] Chaffin M(2017)The WISDOM Study: breaking the deadlock in the breast cancer screening debate Npj Breast Cancer 3 1-7

[3] Aragam KG(2019)Clinical use of current polygenic risk scores may exacerbate health disparities Nat Genet 51 584-1884

[4] Haas ME(2021)Responsible use of polygenic risk scores in the clinic: potential benefits, risks and gaps Nat Med 27 1876-1188

[5] Roselli C(2022)How Communicating Polygenic and Clinical Risk for Atherosclerotic Cardiovascular Disease Impacts Health Behavior: an Observational Follow-up Study Circ Genomic Precis Med 0 CIRCGEN.121.003459-424

[6] Choi SH(2016)Incorporating a Genetic Risk Score Into Coronary Heart Disease Risk Estimates Circulation. 133 1181-87

[7] Esserman LJ(2015)Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology Genet Med 17 405-280

[8] Martin AR(2021)Design and user experience testing of a polygenic score report: a qualitative study of prospective users BMC Med Genet 14 238-1088

[9] Kanai M(2022)Why do people seek out polygenic risk scores for complex disorders, and how do they understand and react to results? Eur J Hum Genet 30 81-618

[10] Kamatani Y(2012)Communicating risk BMJ. 344 270-482