机构:Center for Integrative Chemical Biology and Drug Discovery,Division of Chemical Biology and Medicinal Chemistry
Kimberly D Barnash
Lindsey I James
论文数: 0引用数: 0
h-index: 0
机构:Center for Integrative Chemical Biology and Drug Discovery,Division of Chemical Biology and Medicinal Chemistry
Lindsey I James
Stephen V Frye
论文数: 0引用数: 0
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机构:Center for Integrative Chemical Biology and Drug Discovery,Division of Chemical Biology and Medicinal Chemistry
Stephen V Frye
机构:
[1] Center for Integrative Chemical Biology and Drug Discovery,Division of Chemical Biology and Medicinal Chemistry
[2] UNC Eshelman School of Pharmacy,undefined
[3] University of North Carolina at Chapel Hill,undefined
来源:
Nature Chemical Biology
|
2017年
/
13卷
关键词:
D O I:
暂无
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学科分类号:
摘要:
Selection of molecular targets based on disease understanding is a dominant paradigm in drug discovery. We argue that a focus on classes of targets with central roles in biology provides a complementary approach that has higher quality outcomes in early discovery efforts.
机构:Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
Chen, Xiu-Ping
Du, Guan-Hua
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机构:
Chinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
Peking Union Med Coll, Beijing 100050, Peoples R ChinaChinese Acad Med Sci, Inst Mat Med, Beijing 100050, Peoples R China
Du, Guan-Hua
DRUG DISCOVERIES AND THERAPEUTICS,
2007,
1
(01):
: 23
-
29
机构:
Univ N Carolina, Div Chem Biol & Med Chem, Eshelman Sch Pharm, Chapel Hill, NC 27599 USAUniv N Carolina, Div Chem Biol & Med Chem, Eshelman Sch Pharm, Chapel Hill, NC 27599 USA
Sekaran, Vijay
Soares, Joana
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机构:
Univ N Carolina, Div Chem Biol & Med Chem, Eshelman Sch Pharm, Chapel Hill, NC 27599 USAUniv N Carolina, Div Chem Biol & Med Chem, Eshelman Sch Pharm, Chapel Hill, NC 27599 USA
Soares, Joana
Jarstfer, Michael B.
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h-index: 0
机构:
Univ N Carolina, Div Chem Biol & Med Chem, Eshelman Sch Pharm, Chapel Hill, NC 27599 USAUniv N Carolina, Div Chem Biol & Med Chem, Eshelman Sch Pharm, Chapel Hill, NC 27599 USA
机构:
Wadsworth Center,New York State Department of HealthWadsworth Center,New York State Department of Health
Matthew Brecher
Jing Zhang
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h-index: 0
机构:
Wadsworth Center,New York State Department of HealthWadsworth Center,New York State Department of Health
Jing Zhang
Hongmin Li
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机构:
Wadsworth Center,New York State Department of Health
Department of Biomedical Sciences,School of Public Health,State University of New YorkWadsworth Center,New York State Department of Health