Mechanisms of Disease: nicotine—a review of its actions in the context of gastrointestinal disease

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作者
Gareth AO Thomas
John Rhodes
John R Ingram
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[1] at the University Hospital of Wales,Consultant Gastroenterologist Department of Gastroenterology
[2] at the University Hospital of Wales,Professor emeritus Department of Gastroenterology
[3] at the University Hospital of Wales,doctor in the Department of Gastroenterology
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摘要
Smoking can have a detrimental and beneficial effect on gastrointestinal disease—it has such a 'polarizing effect' in patients with Crohn's disease and ulcerative colitis. Studies in tobacco smokers have made it difficult to identify which agents are responsible for these effects, but work on the action of nicotine alone might help to explain some of the positive and negative links between smoking and gastrointestinal disease.
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页码:536 / 544
页数:8
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