Structural basis for regulation of Arp2/3 complex by GMF

被引：0
作者：
Qing Luan
Brad J Nolen
机构：
[1] Institute of Molecular Biology,Department of Chemistry and Biochemistry
[2] University of Oregon,undefined
[3] University of Oregon,undefined
来源：
Nature Structural & Molecular Biology | 2013年 / 20卷
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摘要：
The Arp2/3 complex regulates the actin cytoskeleton by nucleating branched actin filaments in response to cellular signals and is in turn controlled by regulators including GMF. The crystal structure of GMF bound to Arp2/3 provides insight into how GMF inhibits actin nucleation and dissembles branches.
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页码：1062 / 1068
页数：6
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