Successful neoadjuvant synchronous chemo- and radiotherapy for disseminated primary intracranial choriocarcinoma: case report

被引：0
作者：
Teruyoshi Kageji
Shinji Nagahiro
Kazuhito Matsuzaki
Yasuhiko Kanematsu
Minoru Nakatani
Yasuhiko Okamoto
Tsutomu Watanabe
机构：
[1] School of Medicine,Department of Neurosurgery and Pediatrics
[2] The University of Tokushima,undefined
来源：
Journal of Neuro-Oncology | 2007年 / 83卷
关键词：
Choriocarcinoma; Intracranial tumor; Germ cell tumor; Chemotherapy; Radiation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
We report a 17-year-old male with disseminated intracranial choriocarcinoma at the basal ganglia whose consciousness level was very low at diagnosis. He received neoadjuvant therapy (NAT) consisting of combined chemo- and radiotherapy prior to radical excision of the tumor. Postoperatively he was treated with three courses of high-dose chemotherapy (carboplatin (CBDCA), methotrexate (MTX), and etoposide (VP-16)) and peripheral blood stem-cell transplantation. This combination of therapies resulted in tumor regression on MRI and remarkable improvement in his neurological condition. Ours is the first report of the effectiveness of NAT followed by radical surgery in a patient with disseminated primary intracranial choriocarcinoma.
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页码：199 / 204
页数：5
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