TAS-116 inhibits oncogenic KIT signalling on the Golgi in both imatinib-naïve and imatinib-resistant gastrointestinal stromal tumours

被引:0
作者
Yurina Saito
Tsuyoshi Takahashi
Yuuki Obata
Toshirou Nishida
Shuichi Ohkubo
Fumio Nakagawa
Satoshi Serada
Minoru Fujimoto
Tomoharu Ohkawara
Takahiko Nishigaki
Takahito Sugase
Masahiro Koh
Tomo Ishida
Koji Tanaka
Yasuhiro Miyazaki
Tomoki Makino
Yukinori Kurokawa
Kiyokazu Nakajima
Makoto Yamasaki
Seiichi Hirota
Tetsuji Naka
Masaki Mori
Yuichiro Doki
机构
[1] Osaka University Graduate School of Medicine,Department of Gastroenterological Surgery
[2] National Cancer Center Hospital,Department of Surgical Pathology
[3] Taiho Pharmaceutical Co. Ltd,undefined
[4] Kochi Medical School Hospital,undefined
[5] Hyogo College of Medicine,undefined
来源
British Journal of Cancer | 2020年 / 122卷
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页码:658 / 667
页数:9
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[1]  
DeMatteo RP(2000)Two hundred gastrointestinal stromal tumors: recurrence patterns and prognostic factors for survival Ann. Surg. 231 51-58
[2]  
Lewis JJ(1998)Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors Science 279 577-580
[3]  
Leung D(2004)Biology of gastrointestinal stromal tumors J. Clin. Oncol. 22 3813-3825
[4]  
Mudan SS(2010)NCCN task force report: update on the management of patients with gastrointestinal stromal tumors J. Natl Compr. Canc. Netw. 8 1-41
[5]  
Woodruff JM(2004)Use of c-KIT/ PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group Eur. J. Cancer 40 689-695
[6]  
Brennan MF(2003)Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor J. Clin. Oncol. 21 4342-4349
[7]  
Hirota S(2009)Resistance to tyrosine kinase inhibitors in gastrointestinal stromal tumors Clin. Cancer Res. 15 7510-7518
[8]  
Isozaki K(2006)Efficacy and safety of sunitinib in patients with advanced gastrointestinal stromal tumour after failure of imatinib: a randomised controlled trial Lancet 368 1329-1338
[9]  
Moriyama Y(2013)Efficacy and safety of regorafenib for advanced gastrointestinal stromal tumours after failure of imatinib and sunitinib (GRID): an international, multicentre, randomised, placebo-controlled, phase 3 trial Lancet 381 295-302
[10]  
Hashimoto K(2013)Selecting tyrosine kinase inhibitors for gastrointestinal stromal tumor with secondary KIT activation-loop domain mutations PLoS ONE 8 E65762-251