SGLT2 Inhibition by Dapagliflozin Attenuates Diabetic Ketoacidosis in Mice with Type-1 Diabetes

被引:0
作者
Huan Chen
Yochai Birnbaum
Regina Ye
Hsiu-Chiung Yang
Mandeep Bajaj
Yumei Ye
机构
[1] University of Texas Medical Branch,The Department of Biochemistry and Molecular Biology
[2] First Affiliated Hospital of Nanjing Medical University,Department of Acupuncture
[3] Baylor College of Medicine,The Section of Cardiology, Department of Medicine
[4] BioPharmaceuticals R&D,Research and Early Development Cardiovascular, Renal and Metabolism
[5] AstraZeneca,Section of Endocrinology
[6] Baylor College of Medicine,undefined
来源
Cardiovascular Drugs and Therapy | 2022年 / 36卷
关键词
Diabetes mellitus; Diabetic ketoacidosis; Inflammation; SGLT2 inhibitor; Dehydration;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1091 / 1108
页数:17
相关论文
共 341 条
[1]  
Wiviott SD(2019)Dapagliflozin and cardiovascular outcomes in type 2 diabetes N Engl J Med 380 347-357
[2]  
Raz I(2015)Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes N Engl J Med 373 2117-2128
[3]  
Bonaca MP(2017)Canagliflozin and cardiovascular and renal events in type 2 diabetes N Engl J Med 377 644-657
[4]  
Mosenzon O(2021)Sotagliflozin in patients with diabetes and recent worsening heart failure N Engl J Med 384 117-128
[5]  
Kato ET(2021)Sotagliflozin in patients with diabetes and chronic kidney disease N Engl J Med 384 129-139
[6]  
Cahn A(2019)Dapagliflozin in patients with heart failure and reduced ejection fraction N Engl J Med 381 1995-2008
[7]  
Zinman B(2020)Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes JAMA 323 1353-1368
[8]  
Wanner C(2020)Cardiovascular and renal outcomes with empagliflozin in heart failure N Engl J Med 383 1413-1424
[9]  
Lachin JM(2021)Effects of dapagliflozin on major adverse kidney and cardiovascular events in patients with diabetic and non-diabetic chronic kidney disease: a prespecified analysis from the DAPA-CKD trial Lancet Diabetes Endocrinol 9 22-31
[10]  
Fitchett D(2020)Dapagliflozin in patients with chronic kidney disease N Engl J Med 383 1436-1446