The integrin beta1 modulator Tirofiban prevents adipogenesis and obesity by the overexpression of integrin-linked kinase: a pre-clinical approach in vitro and in vivo

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作者
S. de Frutos
M. Griera
M. Hatem-Vaquero
S. Campillo
E. Gutiérrez-Calabres
D. García-Ayuso
M. Pardo
L. Calleros
M. Rodríguez-Puyol
D. Rodríguez-Puyol
机构
[1] Unidad Fisiología,Departamento de Biología de Sistemas
[2] Facultad de Medicina,undefined
[3] Universidad de Alcalá,undefined
[4] Instituto Ramon Y Cajal de Investigación Sanitaria,undefined
[5] Fundación Renal Iñigo Álvarez de Toledo and RedInRen from Instituto de Salud Carlos III,undefined
[6] and NOVELREN from Comunidad de Madrid,undefined
[7] Graphenano Medical Care S.L.,undefined
[8] Biomedical Research Foundation from Hospital Universitario Príncipe de Asturias,undefined
[9] Instituto de Investigación Sanitaria de Santiago,undefined
[10] Servizo Galego de Saúde,undefined
[11] Nephrology Unit from Hospital Príncipe de Asturias and Department of Medicine from Universidad de Alcalá,undefined
来源
Cell & Bioscience | / 12卷
关键词
Tirofiban; Integrin-beta1; Integrin-linked kinase; AKT; Adipogenesis; Obesity; Hypertrophic adipocyte; Browning; White adipose tissue; Lipolysis; Inflammation;
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