Evaluation of Hepatoprotective Activity of Water-Soluble Polysaccharide Fraction of Stellaria Media L.

被引:0
作者
Ya. V. Gorina
E. V. Saprykina
E. A. Gereng
T. V. Perevozchikova
E. A. Krasnov
E. V. Ivanova
E. A. Fait
O. V. Baranova
机构
[1] the Russian Ministry of Health,Siberian State Medical University
[2] Siberian State Medical University,Central Research Laboratory
来源
Bulletin of Experimental Biology and Medicine | 2013年 / 154卷
关键词
Stellaria media L.; polysaccharides; hepatoprotective activity;
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摘要
Therapy of rats with CCl4 hepatitis with Stellaria media L. water-soluble polysaccharide fraction in a dose of 100 mg/kg reduces serum activities of transaminases (ALT and AST), alkaline phosphatase, bilirubin, and the thymol test values. In the liver, the density of inflammatory infiltration of the organ parenchyma, total count of necrotic hepatocytes, fatty and protein degeneration are reducing. Hence, water-soluble polysaccharide fraction, isolated from the terrestrial part of Stellaria media L., is characterized by hepatoprotective activity.
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页码:645 / 648
页数:3
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