Roles of VEGF-C and Smad4 in the Lymphangiogenesis, Lymphatic Metastasis, and Prognosis in Colon Cancer

[1] Skobe M(2001)Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis Nat Med 7 151-152

[2] Hawighorst T(2010)The effect of the expression of vascular endothelial growth factor (VEGF)-C and VEGF receptor-3 on the clinical outcome in patients with gastric carcinoma Eur J Surg Oncol 36 1172-1179

[3] Jackson DG(2008)Vector-based RNA interference against vascular endothelial growth factor-C inhibits tumor lymphangiogenesis and growth of colorectal cancer in vivo in mice Chin Med J (Engl) 121 439-444

[4] Prevo R(2009)Targeting transforming growth factor-beta signaling in liver metastasis of colon cancer Cancer Lett 277 114-120

[5] Janes L(2010)Antimetastatic role of Smad4 signaling in colorectal cancer Gastroenterology 138 969-980

[6] Velasco P(2006)Tumour microenvironment: TGF-beta: the molecular Jekyll and Hyde of cancer Nat Rev Cancer 6 506-520

[7] Han FH(2005)SMAD4 levels and response to 5-fluorouracil in colorectal cancer Clin Cancer Res 11 6311-6316

[8] Li HM(1999)Higher frequency of Oncogene 18 3098-3103

[9] Zheng DH(2009) gene mutation in human colorectal cancer with distant metastasis CA Cancer J Clin 59 225-249

[10] He YL(2007)Cancer statistics 2009 Colorectal Dis 9 793-800

[1] Skobe M(2001)Induction of tumor lymphangiogenesis by VEGF-C promotes breast cancer metastasis Nat Med 7 151-152

[2] Hawighorst T(2010)The effect of the expression of vascular endothelial growth factor (VEGF)-C and VEGF receptor-3 on the clinical outcome in patients with gastric carcinoma Eur J Surg Oncol 36 1172-1179

[3] Jackson DG(2008)Vector-based RNA interference against vascular endothelial growth factor-C inhibits tumor lymphangiogenesis and growth of colorectal cancer in vivo in mice Chin Med J (Engl) 121 439-444

[4] Prevo R(2009)Targeting transforming growth factor-beta signaling in liver metastasis of colon cancer Cancer Lett 277 114-120

[5] Janes L(2010)Antimetastatic role of Smad4 signaling in colorectal cancer Gastroenterology 138 969-980

[6] Velasco P(2006)Tumour microenvironment: TGF-beta: the molecular Jekyll and Hyde of cancer Nat Rev Cancer 6 506-520

[7] Han FH(2005)SMAD4 levels and response to 5-fluorouracil in colorectal cancer Clin Cancer Res 11 6311-6316

[8] Li HM(1999)Higher frequency of Oncogene 18 3098-3103

[9] Zheng DH(2009) gene mutation in human colorectal cancer with distant metastasis CA Cancer J Clin 59 225-249

[10] He YL(2007)Cancer statistics 2009 Colorectal Dis 9 793-800