High baseline FGF21 levels are associated with poor glucose-lowering efficacy of exenatide in patients with type 2 diabetes

被引:0
作者
Kun Yang
Haining Wang
Rui Wei
Wenhua Xiao
Qing Tian
Chen Wang
Jin Yang
Tianpei Hong
机构
[1] Peking University Third Hospital,Department of Endocrinology and Metabolism
来源
Acta Diabetologica | 2021年 / 58卷
关键词
Fibroblast growth factor 21; Glucagon-like peptide-1 receptor agonist; Therapeutic efficacy; Type 2 diabetes;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:595 / 602
页数:7
相关论文
共 167 条
  • [1] DeFronzo RA(2015)Type 2 diabetes mellitus Nat Rev Dis Primers 1 15019-324
  • [2] Ferrannini E(2013)Glycemic control among patients in China with type 2 diabetes mellitus receiving oral drugs or injectables BMC Publ Health 13 602-S110
  • [3] Groop L(2019)Global and regional diabetes prevalence estimates for 2019 and projections for 2030 and 2045: results from the International Diabetes Federation Diabetes Atlas, 9(th) edition Diabetes Res Clin Pract 157 107843-1705
  • [4] Henry RR(2016)Comparison of clinical outcomes and adverse events associated with glucose-lowering drugs in patients with type 2 diabetes: a meta-analysis JAMA 316 313-1528
  • [5] Herman WH(2020)Pharmacologic approaches to glycemic treatment: standards of medical care in diabetes-2020 Diabetes Care 43 S98-311
  • [6] Holst JJ(2006)The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes Lancet 368 1696-84
  • [7] Ji LN(2011)GLP-1 receptor agonists and HbA1c target of < 7% in type 2 diabetes: meta-analysis of randomized controlled trials Curr Med Res Opin 27 1519-149
  • [8] Lu JM(2014)FGF21-based pharmacotherapy–potential utility for metabolic disorders Trends Endocrinol Metab 25 303-2115
  • [9] Guo XH(2019)Liver-derived fibroblast growth factor 21 mediates effects of glucagon-like peptide-1 in attenuating hepatic glucose output EBioMedicine 41 73-1000
  • [10] Yang WY(2014)Liraglutide suppresses obesity and hyperglycemia associated with increases in hepatic fibroblast growth factor 21 production in KKAy mice Biomed Res Int 2014 751930-795