A Novel Single-Labeled Fluorescent Oligonucleotide Probe for Mercury(II) Ion Detection: Using the Inherent Quenching of Deoxyguanosines

被引：0
作者：
Lei Wang
Jingqi Tian
Hailong Li
Yingwei Zhang
Xuping Sun
机构：
[1] Chinese Academy of Sciences,State Key Lab of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry
[2] Graduate School of the Chinese Academy of Sciences,undefined
来源：
Journal of Fluorescence | 2011年 / 21卷
关键词：
Single-labeled probe; Fluorescence; Oligonucleotide; Mercury(II) ion detection; Quenching;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A novel single-labeled fluorescent oligonucleotide (OND) probe for the detection of nanomolar mercury(II) ion in aqueous solution is developed based on the inherent quenching of deoxyguanosines. The formation of hairpin structure of OND-Hg2+ complex brings deoxyguanosines close to dye, resulting in decreased dye fluorescence due to photoinduced electron transfer from dye to deoxyguanosines.
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页码：1049 / 1052
页数：3
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